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Science 21 January 1977:
Vol. 195. no. 4275, pp. 301 - 302
DOI: 10.1126/science.195.4275.301
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Articles

Leucine 2,3-Aminomutase: A Cobalamin-Dependent Enzyme Present in Bean Seedlings

J. MICHAEL POSTON 1

1 Laboratory of Biochemistry, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland 20014

Leucine 2,3-aminomutase has been demonstrated in extracts of bean seedlings. The activity of this enzyme is stimulated by coenzyme B12 and is inhibited by intrinsic factor. The inhibition is removed by the addition of coenzyme B12. This evidence is consistent with the presence of a cobalamin-dependent enzyme in higher Plants.

Submitted on June 1, 1976
Revised on August 13, 1976


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