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Science 14 January 1977:
Vol. 195. no. 4274, pp. 175 - 177
DOI: 10.1126/science.188133
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Articles

Science, Vol 195, Issue 4274, 175-177
Copyright © 1977 by American Association for the Advancement of Science

articles

Slow persistent infection caused by visna virus: role of host restriction

AT Haase, L Stowring, P Narayan, D Griffin, and D Price

Proviral DNA has been demonstrated by in situ hybridization in foci of cells of a lamb infected with the RNA slow virus visna. A few of these cells also contain the major virion structural antigen p30. This restriction in virus gene expression in the infected animal provides a mechanism for persistence of virus in this chronic infection.


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