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Science 24 December 1976:
Vol. 194. no. 4272, pp. 1427 - 1428
DOI: 10.1126/science.1006308
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Articles

Science, Vol 194, Issue 4272, 1427-1428
Copyright © 1976 by American Association for the Advancement of Science

articles

HLA antigens and corticosteroid response

B Becker, DH Shin, PF Palmberg, and Waltman SR

Compared with normal individuals, patients with primary open-angle glaucoma have increased prevalences of HLA-B12 and B7 antigens and are more responsive to glucocorticoids. Lymphocytes from both ocular normotensive and glaucomatous individuals with the HLA-B12 antigen require significantly (P less than .02) lower concentrations of prednisolone to inhibit phytohemagglutinin-induced transformation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Lack of Association of Histocompatibility Antigens With Primary Open-Angle Glaucoma.
R. Ritch, S. M. Podos, W. Henley, A. Moss, A. L. Southren, and M. Fotino (1978)
Arch Ophthalmol 96, 2204-2206
   Abstract »    PDF »
Intraocular Pressure Response to Topical Epinephrine and HLA-B12.
D. H. Shin, M. A. Kass, and B. Becker (1978)
Arch Ophthalmol 96, 1012-1013
   Abstract »    PDF »


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