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Science 10 December 1976:
Vol. 194. no. 4270, pp. 1171 - 1173
DOI: 10.1126/science.996547
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Articles

Science, Vol 194, Issue 4270, 1171-1173
Copyright © 1976 by American Association for the Advancement of Science

articles

Hypoxanthine-guanine phosphoribosyltransferase mutant glioma cells: diminished monamine oxidase activity

SD Skaper and JE Seegmiller

A defective capability of cultured rat glioma cells to reutilize purine bases (hypoxanthine-guanine phosphoribosyltransferase deficiency) was associated with a reduced capacity to oxidatively deaminate serotonin and tryptamine. The mutant glioma cells were also more sensitive to the cytotoxic effects of serotonin than were normal cells


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Monoamine Oxidase and Criminality: Identifying an Apparent Biological Marker for Antisocial Behavior.
L. ELLIS (1991)
Journal of Research in Crime and Delinquency 28, 227-251
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