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Science 10 December 1976:
Vol. 194. no. 4270, pp. 1169 - 1171
DOI: 10.1126/science.186869
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Articles

Science, Vol 194, Issue 4270, 1169-1171
Copyright © 1976 by American Association for the Advancement of Science

articles

The renin-angiotensin system and thirst: a reevaluation

EM Stricker, WG Bradshaw, and RH McDonald Jr

Systemic injections of renin that stimulate substantial amounts of drinking in nephrectomized rats can produce plasma renin activities that fall well above the physiological range. Furthermore, increases in plasma renin activities that occur in rats with intact kidneys during experimental hypotension appear to be too low to provide the basis for the observed elevations in water intake. These findings question the contribution of the renin-angiotensin system to thirst under normal physiological conditions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Role of renin-angiotensin system in hypotension-evoked thirst: studies with hydralazine.
S. D. Stocker, A. F. Sved, and E. M. Stricker (2000)
Am J Physiol Regulatory Integrative Comp Physiol 279, R576-R585
   Abstract »    Full Text »    PDF »
Peptides and Psychoneuroendocrinology: A Perspective.
C. B. Nemeroff and A. J. Prange Jr (1978)
Arch Gen Psychiatry 35, 999-1010
   Abstract »    PDF »


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