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Science 26 November 1976:
Vol. 194. no. 4268, pp. 965 - 967
DOI: 10.1126/science.982057
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Articles

Science, Vol 194, Issue 4268, 965-967
Copyright © 1976 by American Association for the Advancement of Science

articles

Cannabinoid induced behavioral convulsions in rabbits

P Martin and P Consroe

A population of New Zealand White rabbits has been found to exhibit behavioral convulsions when given low intravenous doses of psychoactive cannabinoids of marijuana. The behavioral convulsions decrease in severity and then disappear after the long-term administration of delta9-tetrahydrocannabinol. The extreme sensitivity of these rabbits to the stimulant action of cannabinoids suggests that the population might serve as a model in studies of the stimulant action of cannabinoids.


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