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Science 26 November 1976:
Vol. 194. no. 4268, pp. 956 - 959
DOI: 10.1126/science.824732
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Articles

Science, Vol 194, Issue 4268, 956-959
Copyright © 1976 by American Association for the Advancement of Science

articles

Photoreceptor mutant of Drosophia: is protein involved in intermediate steps of phototransduction?

WK Paj, SE Istrit, MC Deland, and CF Wu

In norpA mutants of Drosophila melanogaster the phototransduction process is either partially or completely blocked. By using a temperature-sensitive allele, we have found that that norpA mutation has little or no effect on either the rhodopsin-metarhodopsin transition or the machinery of quantum bump production. Thus, the norpA lesion appears to be localized in the intermediate process of phototransduction. Because a temperature-sensitive allele of norpA has been isolated, the norpA gene probably encodes a protein involved in the process.


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