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Science 15 October 1976:
Vol. 194. no. 4262, pp. 334 - 335
DOI: 10.1126/science.968486
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Articles

Science, Vol 194, Issue 4262, 334-335
Copyright © 1976 by American Association for the Advancement of Science

articles

Genetic composition of a high-yielding influenza A virus recombinant: a vaccine strain against "Swine" influenza

P Palese, MB Ritchey, JL Schulman, and ED Kilbourne

Analysis of the RNA migration pattern of a high-yielding influenza virus recombinant, X-53, used in vaccine production, reveals that only the two genes coding for hemagglutinin and neuraminidase antigens were derived from the "swine" influenza virus parent. A/New Jersey/11/76, while six were acquired from the A/PR/8/34 (HON1) parent, donor of the high yield characteristic.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Influenza Pandemics in Perspective.
E. D. Kilbourne (1977)
JAMA 237, 1225-1228
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