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Science 8 October 1976: Vol. 194. no. 4261, pp. 201 - 202 DOI: 10.1126/science.959849
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Articles
Science, Vol 194, Issue 4261, 201-202
Copyright © 1976 by American Association for the Advancement of Science
Nuclear inclusions in Paget's disease of bone
BG Mills
and
FR Singer
The ultrastructure of bone cells was examined in biopsies from 18 patients with Paget's disease of bone and from 60 patients with a variety of other bone diseases. A characteristic nuclear inclusion was found in the osteoclasts of each patient with Paget's disease. The nuclear inclusion most closely resembles viral nucleocapsids of the measles type.
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