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Science 8 October 1976:
Vol. 194. no. 4261, pp. 193 - 195
DOI: 10.1126/science.959847
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Articles

Science, Vol 194, Issue 4261, 193-195
Copyright © 1976 by American Association for the Advancement of Science

articles

Structural basis for ON-and OFF-center responses in retinal ganglion cells

EV Famiglietti Jr and H Kolb

The inner plexiform layer of the mammalian retina has a bisublaminar organization determined by restricted branching of the terminals of cone bipolar cells and dendrites of class I (large) and class II (small) ganglion cells. Comparison of dendritic field diameters and receptive fiedl center sizes of large ganglion cells suggests that neural circuitry in sublamina a conveys "OFF"-center properties and connections in sublamina b "ON"-center properties to retinal ganglion cells.


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