Science 1 October 1976: Vol. 194. no. 4260, pp. 23 - 28 DOI: 10.1126/science.959840

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Articles

Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability.

F. Colotta, P. Allavena, A. Sica, C. Garlanda, and A. Mantovani (2009)
Carcinogenesis 30, 1073-1081
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Nonneuronal {alpha}7-Nicotinic Receptor for Lung Cancer Treatment.

L. Paleari, E. Negri, A. Catassi, M. Cilli, D. Servent, R. D'Angelillo, A. Cesario, P. Russo, and M. Fini (2009)
Am. J. Respir. Crit. Care Med. 179, 1141-1150
 |  Abstract »  |  Full Text »  |  PDF »

Intra-tumor heterogeneity of MLH1 promoter methylation revealed by deep single molecule bisulfite sequencing.

K. E. Varley, D. G. Mutch, T. B. Edmonston, P. J. Goodfellow, and R. D. Mitra (2009)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

A Common Genetic Mechanism in Malignant Bone Marrow Diseases.

R. L. Levine and M. Carroll (2009)
N. Engl. J. Med. 360, 2355-2357
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Evidence for Common Clonal Origin of Multifocal Lung Cancers.

X. Wang, M. Wang, G. T. MacLennan, F. W. Abdul-Karim, J. N. Eble, T. D. Jones, F. Olobatuyi, R. Eisenberg, O. W. Cummings, S. Zhang, et al. (2009)
J Natl Cancer Inst 101, 560-570
 |  Abstract »  |  Full Text »  |  PDF »

Inferring clonal expansion and cancer stem cell dynamics from DNA methylation patterns in colorectal cancers.

K. D. Siegmund, P. Marjoram, Y.-J. Woo, S. Tavare, and D. Shibata (2009)
PNAS 106, 4828-4833
 |  Abstract »  |  Full Text »  |  PDF »

REVIEW PAPER: Cancer Stem Cells and Cancer Nonstem Cells: From Adult Stem Cells or from Reprogramming of Differentiated Somatic Cells.

J. E. Trosko (2009)
Vet. Pathol. 46, 176-193
 |  Abstract »  |  Full Text »  |  PDF »

Association between CCND1 G/A870 Polymorphism, Allele-Specific Amplification, Cyclin D1 Expression, and Survival in Esophageal and Lung Carcinoma.

V. K. Gupta, A. Feber, L. Xi, A. Pennathur, M. Wu, J. D. Luketich, and T. E. Godfrey (2008)
Clin. Cancer Res. 14, 7804-7812
 |  Abstract »  |  Full Text »  |  PDF »

Single Nucleotide Polymorphism-Based Genome-Wide Chromosome Copy Change, Loss of Heterozygosity, and Aneuploidy in Barrett's Esophagus Neoplastic Progression.

X. Li, P. C. Galipeau, C. A. Sanchez, P. L. Blount, C. C. Maley, J. Arnaudo, D. A. Peiffer, D. Pokholok, K. L. Gunderson, and B. J. Reid (2008)
Cancer Prevention Research 1, 413-423
 |  Abstract »  |  Full Text »  |  PDF »

Age-specific incidence of cancer: Phases, transitions, and biological implications.

R. Meza, J. Jeon, S. H. Moolgavkar, and E. G. Luebeck (2008)
PNAS 105, 16284-16289
 |  Abstract »  |  Full Text »  |  PDF »

Chromosomal translocations: revisited yet again.

J. D. Rowley (2008)
Blood 112, 2183-2189
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Single-cell cloning of colon cancer stem cells reveals a multi-lineage differentiation capacity.

L. Vermeulen, M. Todaro, F. de Sousa Mello, M. R. Sprick, K. Kemper, M. Perez Alea, D. J. Richel, G. Stassi, and J. P. Medema (2008)
PNAS 105, 13427-13432
 |  Abstract »  |  Full Text »  |  PDF »

Advances in Chemical Carcinogenesis: A Historical Review and Prospective.

L. A. Loeb and C. C. Harris (2008)
Cancer Res. 68, 6863-6872
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Cancer Risk Assessment and Cancer Prevention: Promises and Challenges.

B. J. Reid (2008)
Cancer Prevention Research 1, 229-232
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Whole Chromosome Alterations Predict Survival in High-Risk Neuroblastoma without MYCN Amplification.

S. Bilke, Q.-R. Chen, J. S. Wei, and J. Khan (2008)
Clin. Cancer Res. 14, 5540-5547
 |  Abstract »  |  Full Text »  |  PDF »

Dissecting out the genetic origins of Barrett's oesophagus.

R. C Fitzgerald (2008)
Gut 57, 1033-1034
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Integrated one- and two-photon imaging platform reveals clonal expansion as a major driver of mutation load.

D. M. Wiktor-Brown, H.-S. Kwon, Y. S. Nam, P. T. C. So, and B. P. Engelward (2008)
PNAS 105, 10314-10319
 |  Abstract »  |  Full Text »  |  PDF »

Cell Lineage Analysis of a Mouse Tumor.

D. Frumkin, A. Wasserstrom, S. Itzkovitz, T. Stern, A. Harmelin, R. Eilam, G. Rechavi, and E. Shapiro (2008)
Cancer Res. 68, 5924-5931
 |  Abstract »  |  Full Text »  |  PDF »

Genomic Alterations Associated with Early Stages of Breast Tumor Metastasis.

R. E. Ellsworth, D. L. Ellsworth, H. L. Patney, B. Deyarmin, J. A. Hooke, B. Love, and C. D. Shriver (2008)
Ann. Surg. Oncol. 15, 1989-1995
 |  Abstract »  |  Full Text »  |  PDF »

Invincible, but Not Invisible: Imaging Approaches Toward In Vivo Detection of Cancer Stem Cells.

L. S. Hart and W. S. El-Deiry (2008)
J. Clin. Oncol. 26, 2901-2910
 |  Abstract »  |  Full Text »  |  PDF »

Crucial Role of Interleukin-4 in the Survival of Colon Cancer Stem Cells.

M. G. Francipane, M. Perez Alea, Y. Lombardo, M. Todaro, J.P. Medema, and G. Stassi (2008)
Cancer Res. 68, 4022-4025
 |  Abstract »  |  Full Text »  |  PDF »

Cancers Exhibit a Mutator Phenotype: Clinical Implications.

L. A. Loeb, J. H. Bielas, R. A. Beckman, and I. W. Bodmer (2008)
Cancer Res. 68, 3551-3557
 |  Abstract »  |  Full Text »  |  PDF »

Distinct effects of the recurrent Mlh1G67R mutation on MMR functions, cancer, and meiosis.

E. Avdievich, C. Reiss, S. J. Scherer, Y. Zhang, S. M. Maier, B. Jin, H. Hou Jr, A. Rosenwald, H. Riedmiller, R. Kucherlapati, et al. (2008)
PNAS 105, 4247-4252
 |  Abstract »  |  Full Text »  |  PDF »

Expansion of a mutated clone: from stem cell to tumour.

S J Leedham and N A Wright (2008)
J. Clin. Pathol. 61, 164-171
 |  Abstract »  |  Full Text »  |  PDF »

Is Breast Tumor Progression Really Linear?.

K. Polyak (2008)
Clin. Cancer Res. 14, 339-341
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High-Resolution Mapping of DNA Breakpoints to Define True Recurrences Among Ipsilateral Breast Cancers.

M. A. Bollet, N. Servant, P. Neuvial, C. Decraene, I. Lebigot, J.-P. Meyniel, Y. De Rycke, A. Savignoni, G. Rigaill, P. Hupe, et al. (2008)
J Natl Cancer Inst 100, 48-58
 |  Abstract »  |  Full Text »  |  PDF »

The Predominant Role of Surgery in the Prevention and New Trends in the Surgical Treatment of Women With BRCA1/2 Mutations.

M. Fatouros, G. Baltoyiannis, and D. H. Roukos (2008)
Ann. Surg. Oncol. 15, 21-33
 |  Abstract »  |  Full Text »  |  PDF »

Clonal Selection of Metastasis within the Life History of a Tumor.

J. E. Talmadge (2007)
Cancer Res. 67, 11471-11475
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APC mutations lead to cytokinetic failures in vitro and tetraploid genotypes in Min mice.

C. M. Caldwell, R. A. Green, and K. B. Kaplan (2007)
J. Cell Biol. 178, 1109-1120
 |  Abstract »  |  Full Text »  |  PDF »

Inferring Somatic Mutation Rates Using the Stop-Enhanced Green Fluorescent Protein Mouse.

S. Ro and B. Rannala (2007)
Genetics 177, 9-16
 |  Abstract »  |  Full Text »  |  PDF »

The Lethal Phenotype of Cancer: The Molecular Basis of Death Due to Malignancy.

R. D. Loberg, D. A. Bradley, S. A. Tomlins, A. M. Chinnaiyan, and K. J. Pienta (2007)
CA Cancer J Clin 57, 225-241
 |  Abstract »  |  Full Text »  |  PDF »

Chromosome instability, chromosome transcriptome, and clonal evolution of tumor cell populations.

C. Gao, K. Furge, J. Koeman, K. Dykema, Y. Su, M. L. Cutler, A. Werts, P. Haak, and G. F. Vande Woude (2007)
PNAS 104, 8995-9000
 |  Abstract »  |  Full Text »  |  PDF »

Tumor Cell-Organ Microenvironment Interactions in the Pathogenesis of Cancer Metastasis.

R. R. Langley and I. J. Fidler (2007)
Endocr. Rev. 28, 297-321
 |  Abstract »  |  Full Text »  |  PDF »

The Significance of c-erbB-2 Overexpression and p53 Expression in Patients With Axillary Lymph Node--Negative Breast Cancer: A Tissue Microarray Study.

S.-S. Ko, Y.-S. Na, C.-S. Yoon, J.-Y. Park, H.-S. Kim, M.-H. Hur, H.-K. Lee, Y.-K. Chun, S.-S. Kang, B.-W. Park, et al. (2007)
International Journal of Surgical Pathology 15, 98-109
 |  Abstract »  |  PDF »

Heterogeneous Breast Tumoroids: An In Vitro Assay for Investigating Cellular Heterogeneity and Drug Delivery.

A. P. Vamvakidou, M. J. Mondrinos, S. P. Petushi, F. U. Garcia, P. I. Lelkes, and A. Tozeren (2007)
J Biomol Screen 12, 13-20
 |  Abstract »  |  PDF »

Identification of Cyclin D1- and Estrogen-Regulated Genes Contributing to Breast Carcinogenesis and Progression.

C. Yang, S. Trent, V. Ionescu-Tiba, L. Lan, T. Shioda, D. Sgroi, and E. V. Schmidt (2006)
Cancer Res. 66, 11649-11658
 |  Abstract »  |  Full Text »  |  PDF »

Baffled by Bafilomycin: An Anticancer Agent That Induces Hypoxia-Inducible Factor-1{alpha} Expression.

G. L. Semenza (2006)
Mol. Pharmacol. 70, 1841-1843
 |  Abstract »  |  Full Text »  |  PDF »

Intratumoral Heterogeneity of HER-2/neu in Invasive Mammary Carcinomas Using Fluorescence In-Situ Hybridization and Tissue Microarray.

S. J. Shin, E. Hyjek, E. Early, and D. M. Knowles (2006)
International Journal of Surgical Pathology 14, 279-284
 |  Abstract »  |  PDF »

On estimating the polyclonal fraction in lineage-marker studies of tumor origin.

M. A. Newton (2006)
Biostat. 7, 503-514
 |  Abstract »  |  Full Text »  |  PDF »

Diagnosis and grading of dysplasia in Barrett's oesophagus..

R D Odze (2006)
J. Clin. Pathol. 59, 1029-1038
 |  Abstract »  |  Full Text »  |  PDF »

Zebrafish Genomic Instability Mutants and Cancer Susceptibility.

J. L. Moore, L. M. Rush, C. Breneman, M.-A. P. K. Mohideen, and K. C. Cheng (2006)
Genetics 174, 585-600
 |  Abstract »  |  Full Text »  |  PDF »

Commentary: Carcinogenesis as Darwinian evolution? Do the math!.

R. A Gatenby (2006)
Int. J. Epidemiol. 35, 1165-1167
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Alternative inclusion of fibroblast growth factor receptor 2 exon IIIc in Dunning prostate tumors reveals unexpected epithelial mesenchymal plasticity.

S. Oltean, B. S. Sorg, T. Albrecht, V. I. Bonano, R. M. Brazas, M. W. Dewhirst, and M. A. Garcia-Blanco (2006)
PNAS 103, 14116-14121
 |  Abstract »  |  Full Text »  |  PDF »

Efficiency of carcinogenesis with and without a mutator mutation.

R. A. Beckman and L. A. Loeb (2006)
PNAS 103, 14140-14145
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Evolution of cooperation among tumor cells.

R. Axelrod, D. E. Axelrod, and K. J. Pienta (2006)
PNAS 103, 13474-13479
 |  Abstract »  |  Full Text »  |  PDF »

Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability.

S. L. Donahue, Q. Lin, S. Cao, and H. E. Ruley (2006)
PNAS 103, 11642-11646
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Promoter Methylation Suggests Epigenetic Progression in Squamous Cell Carcinoma of the Esophagus.

M. Guo, J. Ren, M. G. House, Y. Qi, M. V. Brock, and J. G. Herman (2006)
Clin. Cancer Res. 12, 4515-4522
 |  Abstract »  |  Full Text »  |  PDF »

Phenobarbital Induces Progressive Patterns of GC-Rich and Gene-Specific Altered DNA Methylation in the Liver of Tumor-Prone B6C3F1 Mice.

A. N. Bachman, J. M. Phillips, and J. I. Goodman (2006)
Toxicol. Sci. 91, 393-405
 |  Abstract »  |  Full Text »  |  PDF »

Conditional Coalescent Trees With Two Mutation Rates and Their Application to Genomic Instability.

M. Emily and O. Francois (2006)
Genetics 172, 1809-1820
 |  Abstract »  |  Full Text »  |  PDF »

Reprogramming of replicative senescence in hepatocellular carcinoma-derived cells.

N. Ozturk, E. Erdal, M. Mumcuoglu, K. C. Akcali, O. Yalcin, S. Senturk, A. Arslan-Ergul, B. Gur, I. Yulug, R. Cetin-Atalay, et al. (2006)
PNAS 103, 2178-2183
 |  Abstract »  |  Full Text »  |  PDF »

Use of cytogenetic indicators in radiobiology.

A. S. Rodrigues, N. G. Oliveira, O. M. Gil, A. Leonard, and J. Rueff (2005)
Radiat Prot Dosimetry 115, 455-460
 |  Abstract »  |  Full Text »  |  PDF »

Tumor suppressor genetics.

S. R. Payne and C. J. Kemp (2005)
Carcinogenesis 26, 2031-2045
 |  Abstract »  |  Full Text »  |  PDF »

Negative Clonal Selection in Tumor Evolution.

R. A. Beckman and L. A. Loeb (2005)
Genetics 171, 2123-2131
 |  Abstract »  |  Full Text »  |  PDF »

Glutathione S-Transferase {pi}1 Promotes Tumorigenicity in HCT116 Human Colon Cancer Cells.

D. T. Dang, F. Chen, M. Kohli, C. Rago, J. M. Cummins, and L. H. Dang (2005)
Cancer Res. 65, 9485-9494
 |  Abstract »  |  Full Text »  |  PDF »

Inferring a Tumor Progression Model for Neuroblastoma From Genomic Data.

S. Bilke, Q.-R. Chen, F. Westerman, M. Schwab, D. Catchpoole, and J. Khan (2005)
J. Clin. Oncol. 23, 7322-7331
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Detection of Lung Cancer Cells by Fluorescence In Situ Hybridization: Comparison With Conventional Cytology.

H. Nakamura, I. Aute, N. Kawasaki, M. Taguchi, T. Ohira, and H. Kato (2005)
Chest 128, 906-911
 |  Abstract »  |  Full Text »  |  PDF »

Proliferation and invasion: Plasticity in tumor cells.

C.-F. Gao, Q. Xie, Y.-L. Su, J. Koeman, S. K. Khoo, M. Gustafson, B. S. Knudsen, R. Hay, N. Shinomiya, and G. F. V. Woude (2005)
PNAS 102, 10528-10533
 |  Abstract »  |  Full Text »  |  PDF »

Intrinsic and acquired resistance to EGFR inhibitors in human cancer therapy.

R. Bianco, T. Troiani, G. Tortora, and F. Ciardiello (2005)
Endocr. Relat. Cancer 12, S159-S171
 |  Abstract »  |  Full Text »  |  PDF »

DNA repair gene XRCC1 Arg399Gln polymorphism is associated with increased risk of uterine leiomyoma.

Y.-T. Jeon, J. W. Kim, N.-H. Park, Y.-S. Song, S.-B. Kang, and H.-P. Lee (2005)
Hum. Reprod. 20, 1586-1589
 |  Abstract »  |  Full Text »  |  PDF »

Suppression of Melanotroph Carcinogenesis Leads to Accelerated Progression of Pituitary Anterior Lobe Tumors and Medullary Thyroid Carcinomas in Rb+/- Mice.

Z. Zhou, A. Flesken-Nikitin, C. G. Levine, E. N. Shmidt, J. P. Eng, E. Yu. Nikitina, D. M. Spencer, and A. Yu. Nikitin (2005)
Cancer Res. 65, 787-796
 |  Abstract »  |  Full Text »  |  PDF »

Genomic Progression in Mouse Models for Liver Tumors.

A.D. TWARD, K.D. JONES, S. YANT, M.A. KAY, R. WANG, and J.M. BISHOP (2005)
Cold Spring Harb Symp Quant Biol 70, 217-224
 |  Abstract »  |  PDF »

Drugging the Cancer Kinome: Progress and Challenges in Developing Personalized Molecular Cancer Therapeutics.

P. WORKMAN (2005)
Cold Spring Harb Symp Quant Biol 70, 499-515
 |  Abstract »  |  PDF »

Prognostic Implications of Molecular and Immunohistochemical Profiles of the Rb and p53 Cell Cycle Regulatory Pathways in Primary Non-Small Cell Lung Carcinoma.

L. Burke, D. B. Flieder, D. G. Guinee, E. Brambilla, A. N. Freedman, W. P. Bennett, R. T. Jones, A. Borkowski, N. A. Caporaso, M. Fleming, et al. (2005)
Clin. Cancer Res. 11, 232-241
 |  Abstract »  |  Full Text »  |  PDF »

Intratumoral Patterns of Clonal Evolution in Meningiomas as Defined by Multicolor Interphase Fluorescence in Situ Hybridization (FISH): Is There a Relationship between Histopathologically Benign and Atypical/Anaplastic Lesions?.

J. M. Sayagues, M. D. Tabernero, A. Maillo, A. Espinosa, A. Rasillo, P. Diaz, J. Ciudad, A. Lopez, M. Merino, J. M. Goncalves, et al. (2004)
J. Mol. Diagn. 6, 316-325
 |  Abstract »  |  Full Text »  |  PDF »

Destructive cycles: the role of genomic instability and adaptation in carcinogenesis.

B. L. Schneider and M. Kulesz-Martin (2004)
Carcinogenesis 25, 2033-2044
 |  Abstract »  |  Full Text »  |  PDF »

The Combination of Genetic Instability and Clonal Expansion Predicts Progression to Esophageal Adenocarcinoma.

C. C. Maley, P. C. Galipeau, X. Li, C. A. Sanchez, T. G. Paulson, P. L. Blount, and B. J. Reid (2004)
Cancer Res. 64, 7629-7633
 |  Abstract »  |  Full Text »  |  PDF »

Down-Regulation of Rad51 and Decreased Homologous Recombination in Hypoxic Cancer Cells.

R. S. Bindra, P. J. Schaffer, A. Meng, J. Woo, K. Maseide, M. E. Roth, P. Lizardi, D. W. Hedley, R. G. Bristow, and P. M. Glazer (2004)
Mol. Cell. Biol. 24, 8504-8518
 |  Abstract »  |  Full Text »  |  PDF »

Heterogeneity in the Distribution of RET/PTC Rearrangements within Individual Post-Chernobyl Papillary Thyroid Carcinomas.

K. Unger, H. Zitzelsberger, G. Salvatore, M. Santoro, T. Bogdanova, H. Braselmann, P. Kastner, L. Zurnadzhy, N. Tronko, P. Hutzler, et al. (2004)
J. Clin. Endocrinol. Metab. 89, 4272-4279
 |  Abstract »  |  Full Text »  |  PDF »

Cancer Prevention Strategies That Address the Evolutionary Dynamics of Neoplastic Cells: Simulating Benign Cell Boosters and Selection for Chemosensitivity.

C. C. Maley, B. J. Reid, and S. Forrest (2004)
Cancer Epidemiol. Biomarkers Prev. 13, 1375-1384
 |  Abstract »  |  Full Text »  |  PDF »

Oncogenes and Tumor Suppressor Genes in Breast Cancer: Potential Diagnostic and Therapeutic Applications.

C. Osborne, P. Wilson, and D. Tripathy (2004)
Oncologist 9, 361-377
 |  Abstract »  |  Full Text »  |  PDF »

DNA end joining becomes less efficient and more error-prone during cellular senescence.

A. Seluanov, D. Mittelman, O. M. Pereira-Smith, J. H. Wilson, and V. Gorbunova (2004)
PNAS 101, 7624-7629
 |  Abstract »  |  Full Text »  |  PDF »

Selectively Advantageous Mutations and Hitchhikers in Neoplasms: p16 Lesions Are Selected in Barrett's Esophagus.

C. C. Maley, P. C. Galipeau, X. Li, C. A. Sanchez, T. G. Paulson, and B. J. Reid (2004)
Cancer Res. 64, 3414-3427
 |  Abstract »  |  Full Text »  |  PDF »

Telomere Length Abnormalities Occur Early in the Initiation of Epithelial Carcinogenesis.

A. K. Meeker, J. L. Hicks, C. A. Iacobuzio-Donahue, E. A. Montgomery, W. H. Westra, T. Y. Chan, B. M. Ronnett, and A. M. De Marzo (2004)
Clin. Cancer Res. 10, 3317-3326
 |  Abstract »  |  Full Text »  |  PDF »

Molecular-genetic characterisation of gliomas that recur as same grade or higher grade tumours.

T J M Hulsebos, D Troost, and S Leenstra (2004)
J. Neurol. Neurosurg. Psychiatry 75, 723-726
 |  Abstract »  |  Full Text »  |  PDF »

Intracellular Patterns of Her-2/neu, ras, and Ploidy Abnormalities in Primary Human Breast Cancers Predict Postoperative Clinical Disease-Free Survival.

S. E. Shackney, C. A. Smith, A. Pollice, K. Brown, R. Day, T. Julian, and J. F. Silverman (2004)
Clin. Cancer Res. 10, 3042-3052
 |  Abstract »  |  Full Text »  |  PDF »

Pretumor Progression: Clonal Evolution of Human Stem Cell Populations.

P. Calabrese, S. Tavare, and D. Shibata (2004)
Am. J. Pathol. 164, 1337-1346
 |  Abstract »  |  Full Text »  |  PDF »

Enhanced Stem Cell Survival in Familial Adenomatous Polyposis.

K.-M. Kim, P. Calabrese, S. Tavare, and D. Shibata (2004)
Am. J. Pathol. 164, 1369-1377
 |  Abstract »  |  Full Text »  |  PDF »

Carcinogen-induced impairment of enzymes for replicative fidelity of DNA and the initiation of tumours.

L. P. Bignold (2004)
Carcinogenesis 25, 299-307
 |  Abstract »  |  Full Text »  |  PDF »

Polyclonal Development of Mouse Mammary Preneoplastic Nodules.

W. C. Kisseberth and E. P. Sandgren (2004)
Cancer Res. 64, 857-863
 |  Abstract »  |  Full Text »  |  PDF »

An Age-Induced Switch to a Hyper-Recombinational State.

M. A. McMurray and D. E. Gottschling (2003)
Science 301, 1908-1911
 |  Abstract »  |  Full Text »  |  PDF »

Aneuploidy and Telomere Attrition Are Independent Determinants of Crisis in SV40-transformed Epithelial Cells.

M. Velicescu, J. Yu, B.-S. Herbert, J. W. Shay, E. Granada, and L. Dubeau (2003)
Cancer Res. 63, 5813-5820
 |  Abstract »  |  Full Text »  |  PDF »

THE MOLECULAR BIOLOGY OF MUCOSAL FIELD CANCERIZATION OF THE HEAD AND NECK.

P. K. Ha and J. A. Califano (2003)
Critical Reviews in Oral Biology & Medicine 14, 363-369
 |  Abstract »  |  Full Text »  |  PDF »

A Genetic Explanation of Slaughter's Concept of Field Cancerization: Evidence and Clinical Implications.

B. J. M. Braakhuis, M. P. Tabor, J. A. Kummer, C. R. Leemans, and R. H. Brakenhoff (2003)
Cancer Res. 63, 1727-1730
 |  Abstract »  |  Full Text »  |  PDF »

The new stem cell biology: something for everyone.

S L Preston, M R Alison, S J Forbes, N C Direkze, R Poulsom, and N A Wright (2003)
Mol. Pathol. 56, 86-96
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in Drosophila myb lead to centrosome amplification and genomic instability.

S.-M. Fung, G. Ramsay, and A. L. Katzen (2003)
Development 129, 347-359
 |  Abstract »  |  Full Text »  |  PDF »

Multiple mutations and cancer.

L. A. Loeb, K. R. Loeb, and J. P. Anderson (2003)
PNAS 100, 776-781
 |  Abstract »  |  Full Text »  |  PDF »

Theory in carcinogenesis and epidemiology.

S Garte (2003)
J Epidemiol Community Health 57, 85
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A Truncated Isoform of the Protein Phosphatase 2A B56{gamma} Regulatory Subunit May Promote Genetic Instability and Cause Tumor Progression.

A. Ito, Y.-i. Koma, K. Watabe, T. Nagano, Y. Endo, H. Nojima, and Y. Kitamura (2003)
Am. J. Pathol. 162, 81-91
 |  Abstract »  |  Full Text »  |  PDF »

Oncologic Mathematics: Evolution of a New Specialty.

R. Y. Chandawarkar and D. P. Guyton (2002)
Arch Surg 137, 1428-1434
 |  Abstract »  |  Full Text »  |  PDF »

Metapopulation dynamics and spatial heterogeneity in cancer.

I. Gonzalez-Garcia, R. V. Sole, and J. Costa (2002)
PNAS 99, 13085-13089
 |  Abstract »  |  Full Text »  |  PDF »

Amplification/Overexpression of a Mitotic Kinase Gene in Human Bladder Cancer.

S. Sen, H. Zhou, R.-D. Zhang, D. S. Yoon, F. Vakar-Lopez, S. Ito, F. Jiang, D. Johnston, H. B. Grossman, A. C. Ruifrok, et al. (2002)
J Natl Cancer Inst 94, 1320-1329
 |  Abstract »  |  Full Text »  |  PDF »

Escherichia coli Strains (ndk) Lacking Nucleoside Diphosphate Kinase Are Powerful Mutators for Base Substitutions and Frameshifts in Mismatch-Repair-Deficient Strains.

J. H. Miller, P. Funchain, W. Clendenin, T. Huang, A. Nguyen, E. Wolff, A. Yeung, J.-H. Chiang, L. Garibyan, M. M. Slupska, et al. (2002)
Genetics 162, 5-13
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Neoplastic Transformation of Human Lung Fibroblast MRC-5 SV2 Cells Induced by Benzo[a]pyrene and Confluence Culture.

H. Zhu and N. Gooderham (2002)
Cancer Res. 62, 4605-4609
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Variable Levels of Chromosomal Instability and Mitotic Spindle Checkpoint Defects in Breast Cancer.

D.-S. Yoon, R. P. Wersto, W. Zhou, F. J. Chrest, E. S. Garrett, T. K. Kwon, and E. Gabrielson (2002)
Am. J. Pathol. 161, 391-397
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Multiple centrosomes arise from tetraploidy checkpoint failure and mitotic centrosome clusters in p53 and RB pocket protein-compromised cells.

F. Borel, O. D. Lohez, F. B. Lacroix, and R. L. Margolis (2002)
PNAS 99, 9819-9824
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Application of Information Theory and Extreme Physical Information to Carcinogenesis.

R. A. Gatenby and B. R. Frieden (2002)
Cancer Res. 62, 3675-3684
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Prognostic Significance of the Metastasis-associated Protein Osteopontin in Human Breast Cancer.

P. S. Rudland, A. Platt-Higgins, M. El-Tanani, S. de Silva Rudland, R. Barraclough, J. H. R. Winstanley, R. Howitt, and C. R. West (2002)
Cancer Res. 62, 3417-3427
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