Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 3 September 1976:
Vol. 193. no. 4256, pp. 915 - 917
DOI: 10.1126/science.948754
Prev | Table of Contents | Next

Articles

Science, Vol 193, Issue 4256, 915-917
Copyright © 1976 by American Association for the Advancement of Science

articles

Acetylcholine hot spots: development on myotubes cultured from aneural limb buds

A Bekoff and WJ Betz

The hypothesis that neural induction plays a role in the development of acetylcholine hot spots (high-sensitivity regions) was tested by electrophysiological mapping of the distribution of acetylcholine sensitivity of myotubes derived from aneural hindlimb buds of chick embryos. Hot spots were found. Therefore, hot spot development is not dependent on prior contact with nerve processes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Essential roles of the acetylcholine receptor {gamma}-subunit in neuromuscular synaptic patterning.
Y. Liu, D. Padgett, M. Takahashi, H. Li, A. Sayeed, R. W. Teichert, B. M. Olivera, J. J. McArdle, W. N. Green, and W. Lin (2008)
Development 135, 1957-1967
   Abstract »    Full Text »    PDF »
Denervated skeletal muscle fibers develop discrete patches of high acetylcholine receptor density.
P. Ko, M. Anderson, and M. Cohen (1977)
Science 196, 540-542
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)