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Science 6 August 1976:
Vol. 193. no. 4252, pp. 496 - 498
DOI: 10.1126/science.941021
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Articles

Science, Vol 193, Issue 4252, 496-498
Copyright © 1976 by American Association for the Advancement of Science

articles

Elevated plasmz zinc: a heritable anomaly

JC Smith, JA Zeller, ED Brown, and SC Ong

An extremely high concentration of zinc in the plasma (hyperzincemia) was found in five out of seven members of one family and in two out of three second generation indiviuals, an indication that the condition is heritable. The excess zinc in the plasma appears to be bound to serum proteins, with no apparent clinical symptoms or abnormalities.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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S. P. Nations, P. J. Boyer, L. A. Love, M. F. Burritt, J. A. Butz, G. I. Wolfe, L. S. Hynan, J. Reisch, and J. R. Trivedi (2008)
Neurology 71, 639-643
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Copper Deficiency Myeloneuropathy Resembling B12 Deficiency: Partial Resolution of MR Imaging Findings with Copper Supplementation.
B.P. Goodman, B.W. Chong, A.C. Patel, G.P. Fletcher, and B.E. Smith (2006)
AJNR Am. J. Neuroradiol. 27, 2112-2114
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Copper Deficiency Myelopathy (Human Swayback).
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Copper deficiency myelopathy produces a clinical picture like subacute combined degeneration.
N. Kumar, J. B. Gross Jr., and J. E. Ahlskog (2004)
Neurology 63, 33-39
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Myelopathy due to copper deficiency.
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Neurology 62, 1655-1656
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Myelopolyneuropathy Due to Copper Deficiency or Zinc Excess?--Reply.
P. Hedera and G. J. Brewer (2004)
Arch Neurol 61, 605
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Myelopolyneuropathy Due to Copper Deficiency or Zinc Excess?.
N. Kumar and J. E. Ahlskog (2004)
Arch Neurol 61, 604-605
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Myelopathy Due to Copper Deficiency Following Gastrointestinal Surgery.
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Arch Neurol 60, 1782-1785
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Myelopolyneuropathy and Pancytopenia Due to Copper Deficiency and High Zinc Levels of Unknown Origin: Further Support for Existence of a New Zinc Overload Syndrome.
P. Hedera, J. K. Fink, P. L. Bockenstedt, and G. J. Brewer (2003)
Arch Neurol 60, 1303-1306
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Myelopathy due to copper deficiency.
N. Kumar, J. B. Gross Jr., and J. E. Ahlskog (2003)
Neurology 61, 273-274
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