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Science 30 July 1976:
Vol. 193. no. 4251, pp. 399 - 401
DOI: 10.1126/science.935874
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Articles

Science, Vol 193, Issue 4251, 399-401
Copyright © 1976 by American Association for the Advancement of Science

articles

Nuclear ghosts: a nonmembranous structural component of mammalian cell nuclei

JM Keller and DE Riley

Electron micrographs of positively stained preparations of nonmembranous ghosts prepared from HeLa cell nuclei have revealed the presence of an array consisting of rodlike and annular structures interconnected by strands sensitive to deoxyribonuclease. This array is believed to be responsible for the spherical shape of nuclei that are free of membrane. In addition, a configurational change in this array may be associated with the cyclic dissolution and reformation of the nuclear envelope that accompanies mitosis in mammalian cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cytoplasmic and Nuclear Architecture in Cells and Tissue: Form, Functions, and Mode of Assembly.
S. Penman, A. Fulton, D. Capco, A. Ben Ze'ev, S. Wittelsberger, and C. F. Tse (1982)
Cold Spring Harb Symp Quant Biol 46, 1013-1028
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