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Science 23 July 1976:
Vol. 193. no. 4250, pp. 335 - 336
DOI: 10.1126/science.935872
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Articles

Science, Vol 193, Issue 4250, 335-336
Copyright © 1976 by American Association for the Advancement of Science

articles

Functional development of prefrontal cortex in rats continues into adolescence

B Kolb and AJ Nonneman

Bilateral removal of the sulcal prefrontal cortex in rats at 60 days of age and older results in aphagia and adipsia, but removal of this area before 60 days of age does not affect food or water regulation. Apparently the development of the role of this neocortical region in feeding and drinking continues well beyond the time of weaning in the rat.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Maturation of Layer V Pyramidal Neurons in the Rat Prefrontal Cortex: Intrinsic Properties and Synaptic Function.
Z.-w. Zhang (2004)
J Neurophysiol 91, 1171-1182
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