Science 23 July 1976: Vol. 193. no. 4250, pp. 317 - 319 DOI: 10.1126/science.1084576

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Articles

Left-Right Determination: Involvement of Molecular Motor KIF3, Cilia, and Nodal Flow.

N. Hirokawa, Y. Tanaka, and Y. Okada (2009)
Cold Spring Harb. Perspect. Biol. 1, a000802
 |  Abstract »  |  Full Text »  |  PDF »

Mutation of Murine Adenylate Kinase 7 Underlies a Primary Ciliary Dyskinesia Phenotype.

A. Fernandez-Gonzalez, S. Kourembanas, T. A. Wyatt, and S. A. Mitsialis (2009)
Am. J. Respir. Cell Mol. Biol. 40, 305-313
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Structural and Functional Lung Disease in Primary Ciliary Dyskinesia.

F. Santamaria, S. Montella, H. A. W. M. Tiddens, G. Guidi, V. Casotti, M. Maglione, and P. A. de Jong (2008)
Chest 134, 351-357
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Primary Ciliary Dyskinesia in Mice Lacking the Novel Ciliary Protein Pcdp1.

L. Lee, D. R. Campagna, J. L. Pinkus, H. Mulhern, T. A. Wyatt, J. H. Sisson, J. A. Pavlik, G. S. Pinkus, and M. D. Fleming (2008)
Mol. Cell. Biol. 28, 949-957
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Making sense of cilia and flagella.

R. D. Sloboda and J. L. Rosenbaum (2007)
J. Cell Biol. 179, 575-582
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Heterotaxia, Congenital Heart Disease, and Primary Ciliary Dyskinesia.

M. Brueckner (2007)
Circulation 115, 2793-2795
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Congenital Heart Disease and Other Heterotaxic Defects in a Large Cohort of Patients With Primary Ciliary Dyskinesia.

M. P. Kennedy, H. Omran, M. W. Leigh, S. Dell, L. Morgan, P. L. Molina, B. V. Robinson, S. L. Minnix, H. Olbrich, T. Severin, et al. (2007)
Circulation 115, 2814-2821
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High-Resolution CT of Patients with Primary Ciliary Dyskinesia.

M. P. Kennedy, P. G. Noone, M. W. Leigh, M. A. Zariwala, S. L. Minnix, M. R. Knowles, and P. L. Molina (2007)
Am. J. Roentgenol. 188, 1232-1238
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Diagnosis of Common Variable Immunodeficiency in a Patient With Primary Ciliary Dyskinesia.

E. W. Skorpinski, S.-J. Kung, E. Yousef, and S. J. McGeady (2007)
Pediatrics 119, e1203-e1205
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The lissencephaly protein Lis1 is present in motile mammalian cilia and requires outer arm dynein for targeting to Chlamydomonas flagella.

L. B. Pedersen, P. Rompolas, S. T. Christensen, J. L. Rosenbaum, and S. M. King (2007)
J. Cell Sci. 120, 858-867
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A common variant in combination with a nonsense mutation in a member of the thioredoxin family causes primary ciliary dyskinesia.

B. Duriez, P. Duquesnoy, E. Escudier, A.-M. Bridoux, D. Escalier, I. Rayet, E. Marcos, A.-M. Vojtek, J.-F. Bercher, and S. Amselem (2007)
PNAS 104, 3336-3341
 |  Abstract »  |  Full Text »  |  PDF »

Cystic Fibrosis and Other Respiratory Diseases of Impaired Mucus Clearance.

A. Livraghi and S. H. Randell (2007)
Toxicol Pathol 35, 116-129
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The roles of cilia in developmental disorders and disease.

B. W. Bisgrove and H. J. Yost (2006)
Development 133, 4131-4143
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DNAH5 Mutations Are a Common Cause of Primary Ciliary Dyskinesia with Outer Dynein Arm Defects.

N. Hornef, H. Olbrich, J. Horvath, M. A. Zariwala, M. Fliegauf, N. T. Loges, J. Wildhaber, P. G. Noone, M. Kennedy, S. E. Antonarakis, et al. (2006)
Am. J. Respir. Crit. Care Med. 174, 120-126
 |  Abstract »  |  Full Text »  |  PDF »

Stigmatization, Physical Illness and Mental Health in Primary Ciliary Dyskinesia.

I. C. McManus, G. F. Stubbings, and N. Martin (2006)
J Health Psychol 11, 467-482
 |  Abstract »  |  PDF »

RPGR is mutated in patients with a complex X linked phenotype combining primary ciliary dyskinesia and retinitis pigmentosa.

A Moore, E Escudier, G Roger, A Tamalet, B Pelosse, S Marlin, A Clement, M Geremek, B Delaisi, A-M Bridoux, et al. (2006)
J. Med. Genet. 43, 326-333
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Calcium at Fertilization and in Early Development.

M. Whitaker (2006)
Physiol Rev 86, 25-88
 |  Abstract »  |  Full Text »  |  PDF »

An incredible decade for the primary cilium: a look at a once-forgotten organelle.

J. R. Davenport and B. K. Yoder (2005)
Am J Physiol Renal Physiol 289, F1159-F1169
 |  Abstract »  |  Full Text »  |  PDF »

Primary Flagellar Abnormality Is Associated With an Increased Rate of Spermatozoa Aneuploidy.

N. Rives, N. Mousset-Simeon, S. Mazurier, and B. Mace (2005)
J Androl 26, 61-69
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Intraflagellar Transport and Cilia-Dependent Renal Disease: The Ciliary Hypothesis of Polycystic Kidney Disease.

G. J. Pazour (2004)
J. Am. Soc. Nephrol. 15, 2528-2536
 |  Abstract »  |  Full Text »  |  PDF »

Mice Deficient in the Axonemal Protein Tektin-t Exhibit Male Infertility and Immotile-Cilium Syndrome Due to Impaired Inner Arm Dynein Function.

H. Tanaka, N. Iguchi, Y. Toyama, K. Kitamura, T. Takahashi, K. Kaseda, M. Maekawa, and Y. Nishimune (2004)
Mol. Cell. Biol. 24, 7958-7964
 |  Abstract »  |  Full Text »  |  PDF »

Immunohistochemical Demonstration of Carbonic Anhydrase Isoenzyme VI (CA VI) Expression in Rat Lower Airways and Lung.

J. S. Leinonen, K. A. Saari, J. M. Seppanen, H. M. Myllyla, and H. J. Rajaniemi (2004)
J. Histochem. Cytochem. 52, 1107-1112
 |  Abstract »  |  Full Text »  |  PDF »

THE EMBRYONIC ORIGINS OF LEFT-RIGHT ASYMMETRY.

M. Levin (2004)
Critical Reviews in Oral Biology & Medicine 15, 197-206
 |  Abstract »  |  Full Text »  |  PDF »

"Cyst-like" structures within the ciliary shafts in children with bronchiectasis.

M. Pifferi, A.M. Cangiotti, D. Caramella, A. Pietrobelli, V. Ragazzo, E. De Marco, P. Macchia, S. Cinti, and A.L. Boner (2004)
Eur. Respir. J. 23, 857-860
 |  Abstract »  |  Full Text »  |  PDF »

Fluid-dynamical basis of the embryonic development of left-right asymmetry in vertebrates.

J. H. E. Cartwright, O. Piro, and I. Tuval (2004)
PNAS 101, 7234-7239
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Regulation of Cilia Assembly and the Relationship to Human Disease.

S. L. Brody (2004)
Am. J. Respir. Cell Mol. Biol. 30, 435-437
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Loci for primary ciliary dyskinesia map to chromosome 16p12.1-12.2 and 15q13.1-15.1 in Faroe Islands and Israeli Druze genetic isolates.

D Jeganathan, R Chodhari, M Meeks, O Faeroe, D Smyth, K Nielsen, I Amirav, A S Luder, H Bisgaard, R M Gardiner, et al. (2004)
J. Med. Genet. 41, 233-240
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Mucociliary transport determined by in vivo microdialysis in the airways of normal and CF mice.

B. R. Grubb, J. H. Jones, and R. C. Boucher (2004)
Am J Physiol Lung Cell Mol Physiol 286, L588-L595
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Primary Ciliary Dyskinesia: Diagnostic and Phenotypic Features.

P. G. Noone, M. W. Leigh, A. Sannuti, S. L. Minnix, J. L. Carson, M. Hazucha, M. A. Zariwala, and M. R. Knowles (2004)
Am. J. Respir. Crit. Care Med. 169, 459-467
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Tales From the Tail: What Do We Really Know About Sperm Motility?.

R. M. Turner (2003)
J Androl 24, 790-803
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RPGR mutation associated with retinitis pigmentosa, impaired hearing, and sinorespiratory infections.

I Zito, S M Downes, R J Patel, M E Cheetham, N D Ebenezer, S A Jenkins, S S Bhattacharya, A R Webster, G E Holder, A C Bird, et al. (2003)
J. Med. Genet. 40, 609-615
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Genotype-phenotype correlations in PCD patients carrying DNAH5 mutations.

A Kispert, M Petry, H Olbrich, A Volz, U-P Ketelsen, J Horvath, R Melkaoui, H Omran, M Zariwala, P G Noone, et al. (2003)
Thorax 58, 552-554
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To beat or not to beat: roles of cilia in development and disease.

I. Ibanez-Tallon, N. Heintz, and H. Omran (2003)
Hum. Mol. Genet. 12, R27-35
 |  Abstract »  |  Full Text »  |  PDF »

A two-cilia model for vertebrate left-right axis specification.

C. J. Tabin and K. J. Vogan (2003)
Genes & Dev. 17, 1-6
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Computer-assisted Analysis Helps Detect Inner Dynein Arm Abnormalities.

E. Escudier, M. Couprie, B. Duriez, F. Roudot-Thoraval, M.-C. Millepied, V. Pruliere-Escabasse, L. Labatte, and A. Coste (2002)
Am. J. Respir. Crit. Care Med. 166, 1257-1262
 |  Abstract »  |  Full Text »  |  PDF »

Primary ciliary dyskinesia.

A Bush, C O'Callaghan, and A Boon (2002)
Arch. Dis. Child. 87, 363-365
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Isolation and Expression of the Human hPF20 Gene Orthologous to Chlamydomonas pf20 . Evaluation as a Candidate for Axonemal Defects of Respiratory Cilia and Sperm Flagella.

G. Pennarun, A.-M. Bridoux, E. Escudier, F. Dastot-Le Moal, V. Cacheux, S. Amselem, and B. Duriez (2002)
Am. J. Respir. Cell Mol. Biol. 26, 362-370
 |  Abstract »  |  Full Text »  |  PDF »

Kartagener's Syndrome in a Dachshund Dog.

J. A. Neil, S. O. Canapp Jr., C. R. Cook, and J. C. Lattimer (2002)
J. Am. Anim. Hosp. Assoc. 38, 45-49
 |  Abstract »  |  Full Text »  |  PDF »

Germline Mutations in an Intermediate Chain Dynein Cause Primary Ciliary Dyskinesia.

M. Zariwala, P. G. Noone, A. Sannuti, S. Minnix, Z. Zhou, M. W. Leigh, M. Hazucha, J. L. Carson, and M. R. Knowles (2001)
Am. J. Respir. Cell Mol. Biol. 25, 577-583
 |  Abstract »  |  Full Text »  |  PDF »

Abnormal Central Complex Is a Marker of Severity in the Presence of Partial Ciliary Defect.

A. Tamalet, A. Clement, F. Roudot-Thoraval, P. Desmarquest, G. Roger, M. Boule, M. C. Millepied, T.{s. A. Baculard, and E. Escudier (2001)
Pediatrics 108, e86-86
 |  Abstract »  |  Full Text »  |  PDF »

Disruption of an inner arm dynein heavy chain gene results in asthenozoospermia and reduced ciliary beat frequency.

J. Neesen, R. Kirschner, M. Ochs, A. Schmiedl, B. Habermann, C. Mueller, A. F. Holstein, T. Nuesslein, I. Adham, and W. Engel (2001)
Hum. Mol. Genet. 10, 1117-1128
 |  Abstract »  |  Full Text »  |  PDF »

Primary ciliary dyskinesia syndrome associated with abnormal ciliary orientation in infants.

E. Biggart, K. Pritchard, R. Wilson, and A. Bush (2001)
Eur. Respir. J. 17, 444-448
 |  Abstract »  |  Full Text »  |  PDF »

Polaris, a Protein Involved in Left-Right Axis Patterning, Localizes to Basal Bodies and Cilia.

P. D. Taulman, C. J. Haycraft, D. F. Balkovetz, and B. K. Yoder (2001)
Mol. Biol. Cell 12, 589-599
 |  Abstract »  |  Full Text »

Homozygosity Mapping of a Gene Locus for Primary Ciliary Dyskinesia on Chromosome 5p and Identification of the Heavy Dynein Chain DNAH5 as a Candidate Gene.

H. Omran, K. Häffner, A. Völkel, J. Kuehr, U.-P. Ketelsen, U.-H. Ross, N. Konietzko, T. Wienker, M. Brandis, and F. Hildebrandt (2000)
Am. J. Respir. Cell Mol. Biol. 23, 696-702
 |  Abstract »  |  Full Text »

Ciliogenesis and Left-Right Axis Defects in Forkhead Factor HFH-4-Null Mice.

S. L. Brody, X. H. Yan, M. K. Wuerffel, S.-K. Song, and S. D. Shapiro (2000)
Am. J. Respir. Cell Mol. Biol. 23, 45-51
 |  Abstract »  |  Full Text »

Severe Bronchiectasis in Patients with "Cystlike" Structures within the Ciliary Shafts.

K. W. T. TSANG, G. TIPOE, J. SUN, J. C. M. HO, B. LAM, L. ZHENG, G. C. OOI, M. IP, and W.-K. LAM (2000)
Am. J. Respir. Crit. Care Med. 161, 1300-1305
 |  Abstract »  |  Full Text »

Conserved and divergent mechanisms in left-right axis formation.

R. D. Burdine and A. F. Schier (2000)
Genes & Dev. 14, 763-776
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A locus for primary ciliary dyskinesia maps to chromosome 19q.

M Meeks, A Walne, S Spiden, H Simpson, H Mussaffi-Georgy, H D Hamam, E L Fehaid, M Cheehab, M Al-Dabbagh, S Polak-Charcon, et al. (2000)
J. Med. Genet. 37, 241-244
 |  Abstract »  |  Full Text »

Failure of fertilization after intracytoplasmic sperm injection in a patient with Kartagener's syndrome and totally immotile spermatozoa: Case Report.

A. Abu-Musa, A. Hannoun, A. Khabbaz, and P. Devroey (1999)
Hum. Reprod. 14, 2517-2518
 |  Abstract »  |  Full Text »  |  PDF »

Forkhead Transcription Factor HFH-4 Expression Is Temporally Related to Ciliogenesis.

E. N. Blatt, X. H. Yan, M. K. Wuerffel, D. L. Hamilos, and S. L. Brody (1999)
Am. J. Respir. Cell Mol. Biol. 21, 168-176
 |  Abstract »  |  Full Text »

Effect of Aerosolized Uridine-5'-Triphosphate on Airway Clearance with Cough in Patients with Primary Ciliary Dyskinesia.

P. G. NOONE, W. D. BENNETT, J. A. REGNIS, K. L. ZEMAN, J. L. CARSON, M. KING, R. C. BOUCHER, and M. R. KNOWLES (1999)
Am. J. Respir. Crit. Care Med. 160, 144-149
 |  Abstract »  |  Full Text »

Situs inversus and embryonic ciliary morphogenesis defects in mouse mutants lacking the KIF3A subunit of kinesin-II.

J. R. Marszalek, P. Ruiz-Lozano, E. Roberts, K. R. Chien, and L. S. B. Goldstein (1999)
PNAS 96, 5043-5048
 |  Abstract »  |  Full Text »  |  PDF »

Intraflagellar Transport: The Eyes Have It.

J. L. Rosenbaum, D. G. Cole, and D. R. Diener (1999)
J. Cell Biol. 144, 385-388
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Targeted deletion of the ATP binding domain of left-right dynein confirms its role in specifying development of left-right asymmetries.

D. Supp, M Brueckner, M. Kuehn, D. Witte, L. Lowe, J McGrath, J Corrales, and S. Potter (1999)
Development 126, 5495-5504
 |  Abstract »  |  PDF »

Assisted reproduction for infertile patients with 9+0 immotile spermatozoa associated with autosomal dominant polycystic kidney disease.

H. Okada, H. Fujioka, N. Tatsumi, M. Fujisawa, K. Gohji, S. Arakawa, H. Kato, S.-I. Kobayashi, S. Isojima, and S. Kamidono (1999)
Hum. Reprod. 14, 110-113
 |  Abstract »  |  Full Text »  |  PDF »

Genetics and pulmonary medicine bullet  6: Immotile cilia syndrome: past, present, and prospects for the future.

B A Afzelius (1998)
Thorax 53, 894-897
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The compulsion of chirality: toward an understanding of left-right asymmetry.

M. Levin and M. Mercola (1998)
Genes & Dev. 12, 763-769
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Results of Tympanoplasty in Children With Primary Ciliary Dyskinesia.

F. Denoyelle, G. Roger, V. Ducroz, E. Escudier, B. Fauroux, and E. N. Garabedian (1998)
Arch Otolaryngol Head Neck Surg 124, 177-179
 |  Abstract »  |  Full Text »  |  PDF »

Complementary Deoxyribonucleic Acid Cloning and Characterization of a Putative Human Axonemal Dynein Light Chain Gene.

K. Kastury, W. E. Taylor, R. Shen, S. Arver, M. Gutierrez, C. E. Fisher, P. J. Coucke, P. Van Hauwe, G. Van Camp, and S. Bhasin (1997)
J. Clin. Endocrinol. Metab. 82, 3047-3053
 |  Abstract »  |  Full Text »  |  PDF »

Kartagener's Syndrome: Clinical Presentation and Cardiosurgical Aspects.

T. Tkebuchava, U. Niederhauser, W. Weder, L. K. von Segesser, U. Bauersfeld, H. Felix, M. Lachat, and M. I. Turina (1996)
Ann. Thorac. Surg. 62, 1474-1479
 |  Abstract »  |  Full Text »

Grand Rounds - Hammersmith Hospital Late presentation of Kartagener's syndrome Consequences of ciliary dysfunction.

M Perraudeau (1994)
BMJ 308, 519
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Reversal of left-right asymmetry: a situs inversus mutation.

T Yokoyama, N. Copeland, N. Jenkins, C. Montgomery, F. Elder, and P. Overbeek (1993)
Science 260, 679-682
 |  Abstract »  |  PDF »

Characterization of a Chemotactic Defect in Patients With Kartagener Syndrome.

R. J. Walter, J. R. Danielson, and H. M. Reyes (1990)
Arch Otolaryngol Head Neck Surg 116, 465-469
 |  Abstract »  |  PDF »

Animals in Research.

S. K. Katz (1989)
JAMA 262, 3404-3405
 |  Abstract »  |  PDF »

Abnormal Axonemes in X-linked Retinitis Pigmentosa.

D. G. Hunter, G. A. Fishman, and F. L. Kretzer (1988)
Arch Ophthalmol 106, 362-368
 |  Abstract »  |  PDF »

Tobacco Smoke and Lung Disease: Who Is Susceptible?.

C. C. HARRIS (1986)
Ann Intern Med 105, 607-609
 |  Abstract »  |  PDF »

Kartagener's Syndrome: A Blinded, Controlled Study of Cilia Ultrastructure.

R. D. Eavey, J. B. Nadol Jr, L. B. Holmes, N. M. Laird, A. Lapey, M. P. Joseph, and M. Strome (1986)
Arch Otolaryngol Head Neck Surg 112, 646-650
 |  Abstract »  |  PDF »

Kartagener's Syndrome.

J. H. Woodring, J. M. Royer, and D. McDonagh (1982)
JAMA 247, 2814-2816
 |  Abstract »  |  PDF »

Radioisotopic Method for Measurement of Nasal Mucociliary Activity.

J. Karja, J. Nuutinen, and P. Karjalainen (1982)
Arch Otolaryngol Head Neck Surg 108, 99-101
 |  Abstract »  |  PDF »

Disorders of Phagocyte Chemotaxis.

J. I. GALLIN, D. G. WRIGHT, H. L. MALECH, J. M. DAVIS, M. S. KLEMPNER, and C. H. KIRKPATRICK (1980)
Ann Intern Med 92, 520-538
 |  Abstract »  |  PDF »

Dysmorphology of Cilia: Association With Chronic Suppurative Respiratory Disease.

H. B. Neustein, J. Church, and S. Cohen (1979)
JAMA 241, 2423
 |  Abstract »  |  PDF »

The Missing Cilia.

H. T. Ricketts (1976)
JAMA 236, 1733
 |  Abstract »  |  PDF »

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