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Science 9 July 1976:
Vol. 193. no. 4248, pp. 161 - 162
DOI: 10.1126/science.945610
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Articles

Science, Vol 193, Issue 4248, 161-162
Copyright © 1976 by American Association for the Advancement of Science

articles

Genetic predisposition and stress-induced hypertension

R Friedman and J Iwai

When chronically exposed to an approach-avoidance conflict, rats with a genetic susceptibility to hypertension showed persisten elevations in systolic blood pressure, but rats with a genetic resistance to hypertension did not. Hence, psychic stress is selectively efficacious in producing hypertensive effects depending on genetic predisposition of the animal.


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Neuroendocrine profiling in inherited stress-induced arterial hypertension rat strain with stress-sensitive arterial hypertension.
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Baroreceptor activation reduces reactivity to noxious stimulation: implications for hypertension.
B. Dworkin, R. Filewich, N. Miller, N Craigmyle, and T. Pickering (1979)
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Science. ISSN 0036-8075 (print), 1095-9203 (online)