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Science 2 July 1976:
Vol. 193. no. 4247, pp. 53 - 55
DOI: 10.1126/science.132701
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Articles

Science, Vol 193, Issue 4247, 53-55
Copyright © 1976 by American Association for the Advancement of Science

articles

Expression of C4 on human lymphoid cells and possible involvement in immune recognition phenomena

S Ferrone, MA Pellegrino, and NR Cooper

Immunochemical studies revealed the presence of the fourth component of complement (C4) on surfaces of human lymphoid cells. Antiserums to C4 inhibited the mixed lymphocyte reaction and the mitogenic response to phytohemagglutinin, suggesting a role for membrane-associated C4 in the afferent phase of immune recognition phenomena.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetics and Serology of HL-A-linked Human Ia Antigens.
C. J. Barnstable, E. A. Jones, W. F. Bodmer, J. G. Bodmer, B. Arce-Gomez, D. Snary, and M. J. Crumpton (1977)
Cold Spring Harb Symp Quant Biol 41, 443-455
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Science. ISSN 0036-8075 (print), 1095-9203 (online)