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Science 7 May 1976:
Vol. 192. no. 4239, pp. 565 - 567
DOI: 10.1126/science.1257793
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Articles

Science, Vol 192, Issue 4239, 565-567
Copyright © 1976 by American Association for the Advancement of Science

articles

Antiserum to somatostatin prevents stress-induced inhibition of growth hormone secretion in the rat

LC Terry, JO Willoughby, P Braseau, JB Martin, and Y Patel

Plasma growth hormone levels fall and remain low for several hours after stress in the rat. When antiserums to somatostatin are administered to rats prior to stress, growth hormone secretory pulses are partially restored. The results provide evidence that circulating somatostatin plays a prominent role in stress-induced inhibition of growth hormone secretion in the rat.


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Peptides and Psychoneuroendocrinology: A Perspective.
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Somatostatin: Its Possible Role in Carbohydrate Homeostasis and the Treatment of Diabetes Mellitus.
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