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Science 19 March 1976:
Vol. 191. no. 4232, pp. 1180 - 1183
DOI: 10.1126/science.1062861
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Articles

Science, Vol 191, Issue 4232, 1180-1183
Copyright © 1976 by American Association for the Advancement of Science

articles

Specificity of naturally occurring antibody in normal gibbon serum

T Aoki, M Liu, MJ Walling, GS Bushar, PB Brandchaft, and TG Kawakami

Gibbon natural antibody examined by immunoelectron microscopy reacted with the entire envelope of type C virus and with areas on the cell surface equivalent to or smaller than the diameter of a virion in gibbon and human culture cells infected with or releasing type C viruses. The antibody activity was absorbed completely by two cell cultures infected with gibbon ape leukemia virus and by the virus itself, and partially by normal gibbon spleen cells and dog thymus-derived cells infected with baboon endogenous type C virus, and fresh white blood cells obtained from a patient with chronic myelogenous leukemia in acute blastic crisis.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)