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Science 30 January 1976:
Vol. 191. no. 4225, pp. 385 - 388
DOI: 10.1126/science.1082167
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Articles

Science, Vol 191, Issue 4225, 385-388
Copyright © 1976 by American Association for the Advancement of Science

articles

Activation of transplant immunity: effect of donor leukocytes on thyroid allograft rejection

DW Talmage, G Dart, J Radovich, and KJ Lafferty

The survival of thyroid allografts in mice was prolonged by either holding the grafts in vitro culture for 20 to 27 days or by cobalt-60 irradiation of the donor 2 days before transplantation with or without the intravenous injection of colloidal carbon just before removing the thyroid from the donor. In both cases the rejection process was restored by an intravenous injection of recipients with living peritoneal exudate cells (50 to 80 percent macrophages) syngeneic to the thyroid donor.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Critical Requirement for Graft Passenger Leukocytes in Allograft Tolerance Induced by Donor Blood Transfusion.
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Fibroblasts as efficient antigen-presenting cells in lymphoid organs.
T. Kundig, M. Bachmann, C DiPaolo, J. Simard, M Battegay, H Lother, A Gessner, K Kuhlcke, P. Ohashi, H Hengartner, et al. (1995)
Science 268, 1343-1347
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Transplantation Immunology.
C. H. Kirkpatrick (1987)
JAMA 258, 2993-3000
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Prolongation of rat islet allograft survival by direct ultraviolet irradiation of the graft.
H Lau, K Reemtsma, and M. Hardy (1984)
Science 223, 607-609
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Prolongation of islet xenograft survival without continuous immunosuppression.
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Prolongation of islet allograft survival following in vitro culture (24 degrees C) and a single injection of ALS.
P. Lacy, J. Davie, and E. Finke (1979)
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Effect of oxygen pressure during culture on survival of mouse thyroid allografts.
D. Talmage and G. Dart (1978)
Science 200, 1066-1067
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Cellular Recognition of Major Histocompatibility Complex Antigens.
F. H. Bach, M. L. Bach, O. J. Kuperman, H. W. Sollinger, and P. M. Sondel (1977)
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