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ArticlesCopyright © 1975 by American Association for the Advancement of Science
Thymus: central role in the immune system of the frog
In the leopard frog (Rana pipiens), the thymus profoundly influences immunologic development by providing virtually all the progenitor lymphocytic cells for the bone marrow and other peripheral lymphoid organs. The thymus houses a self-perpetuating population of lymphopoietic cells that originally self-differentiated in that gland.
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Science. ISSN 0036-8075 (print), 1095-9203 (online)