Related Content
Search Google Scholar for:
|
|
Science 5 December 1975: Vol. 190. no. 4218, pp. 994 - 997 DOI: 10.1126/science.1237932
|
|
Articles
Science, Vol 190, Issue 4218, 994-997
Copyright © 1975 by American Association for the Advancement of Science
Stage-specific switches in histone synthesis during embryogenesis of the sea urchin
LH Cohen,
KM Newrock,
and
A Zweidler
Histones H2A and H2B of the sea urchin embryo have been resolved by new methods into components that are synthesized at different stages of development. One form of H2A and one form of H2B are synthesized only during the period from fertilization to the blastula stage. Subsequently, two other types of H2A and H2B molecules are synthesized. In addition, a histonelike protein was detected which is synthesized only from fertilization until the 16-cell stage when the synthesis of still another H2A-like protein begins. None of the late-appearing forms are derived from histone polypeptide chains synthesized earlier in development. Since the early components do not disappear after their synthesis stops, these modulations of histone synthesis lead to an increase in histone multiplicity, concomitant with the beginning of cell diversification and a decrease in cell division rate.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Probing the Conformation of Nucleosome Linker DNA in Situ with Pyrimidine Dimer Formation.
- J. R. Pehrson and J. R. Pehrson (1995)
J. Biol. Chem.
270, 22440-22444
| Abstract »
| Full Text »
| PDF »
- Regulation of Histone Gene Expression.
- M. Busslinger, D. Schumperli, and M.L. Birnstiel (1985)
Cold Spring Harb Symp Quant Biol
50, 665-670
| Abstract »
| PDF »
- Activation of dormant genes in specialized cells.
- M. DiBerardino, N. Hoffner, and L. Etkin (1984)
Science
224, 946-952
| Abstract »
| PDF »
- Gene expression in eukaryotes.
- D. Brown (1981)
Science
211, 667-674
| Abstract »
| PDF »
- Histone gene expression: progeny of isolated early blastomeres in culture make the same change as in the embryo.
- R. Arceci and P. Gross (1980)
Science
209, 607-609
| Abstract »
| PDF »
- Nucleosomes, Histone Interactions, and the Role of Histones H3 and H4.
- E. M. Bradbury, T. Moss, H. Hayashi, R. P. Hjelm, P. Suau, R. M. Stephens, J. P. Baldwin, and C. Crane-Robinson (1978)
Cold Spring Harb Symp Quant Biol
42, 277-286
| Abstract »
| PDF »
- Immunological Probes for Chromatin Structure.
- M. Bustin, P. D. Kurth, E. N. Moudrianakis, D. Goldblatt, R. Sperling, and W. B. Rizzo (1978)
Cold Spring Harb Symp Quant Biol
42, 379-388
| Abstract »
| PDF »
- Histone Changes during Chromatin Remodeling in Embryogenesis.
- K. M. Newrock, C. R. Alfageme, R. V. Nardi, and L. H. Cohen (1978)
Cold Spring Harb Symp Quant Biol
42, 421-431
| Abstract »
| PDF »
- Histones and Chromatin Structure in Tetrahymena Macro- and Micronuclei.
- M. A. Gorovsky, C. Glover, C. A. Johmann, J. B. Keevert, D. J. Mathis, and M. Samuelson (1978)
Cold Spring Harb Symp Quant Biol
42, 493-503
| Abstract »
| PDF »
- The Organization of the Histone Genes in Drosophila melanogaster: Functional and Evolutionary Implications.
- R. P. Lifton, M. L. Goldberg, R. W. Karp, and D. S. Hogness (1978)
Cold Spring Harb Symp Quant Biol
42, 1047-1051
| Abstract »
| PDF »
- The Histone H4 Gene of Strongylocentrotus purpuratus: DNA and mRNA Sequences at the 5' End.
- M. Grunstein and J. E. Grunstein (1978)
Cold Spring Harb Symp Quant Biol
42, 1083-1092
| Abstract »
| PDF »
- Histone Gene Heterogeneity in the Sea Urchin Strongylocentrotus Purpuratus.
- E. S. Weinberg, G. C. Overton, M. B. Hendricks, K. M. Newrock, and L. H. Cohen (1978)
Cold Spring Harb Symp Quant Biol
42, 1093-1100
| Abstract »
| PDF »
- Chromosomal subunits in active genes have an altered conformation.
- H Weintraub and M Groudine (1976)
Science
193, 848-856
| Abstract »
| PDF »
|
|