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Science 28 November 1975:
Vol. 190. no. 4217, pp. 886 - 888
DOI: 10.1126/science.52892
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Articles

Science, Vol 190, Issue 4217, 886-888
Copyright © 1975 by American Association for the Advancement of Science

articles

Evolution of type C viral genes: origin of feline leukemia virus

RE Benveniste, CJ Sherr, and GJ Todaro

Reiterated gene sequences related to the RNA of feline leukemia virus (FeLV) are detected in all tissues of domestic cats and their close Felis relatives but not in more distantly related Felis species. Partially homologous viral gene sequences are found in rodent, and particularly rat, DNA. Together with the immunologic relationships observed between FeLV and endogenous rodent type C viruses, the results lead to the conclusion that FeLV-related genes were transmitted from a rodent to cat ancestor and have been perpetuated in the germ line of cats.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Insertional Polymorphisms of Endogenous Feline Leukemia Viruses.
A. L. Roca, W. G. Nash, J. C. Menninger, W. J. Murphy, and S. J. O'Brien (2005)
J. Virol. 79, 3979-3986
   Abstract »    Full Text »    PDF »
Genomically Intact Endogenous Feline Leukemia Viruses of Recent Origin.
A. L. Roca, J. Pecon-Slattery, and S. J. O'Brien (2004)
J. Virol. 78, 4370-4375
   Abstract »    Full Text »    PDF »
Feline Pit2 Functions as a Receptor for Subgroup B Feline Leukemia Viruses.
M. M. Anderson, A. S. Lauring, S. Robertson, C. Dirks, and J. Overbaugh (2001)
J. Virol. 75, 10563-10572
   Abstract »    Full Text »    PDF »
Receptors and Entry Cofactors for Retroviruses Include Single and Multiple Transmembrane-Spanning Proteins as well as Newly Described Glycophosphatidylinositol-Anchored and Secreted Proteins.
J. Overbaugh, A. D. Miller, and M. V. Eiden (2001)
Microbiol. Mol. Biol. Rev. 65, 371-389
   Abstract »    Full Text »    PDF »
Long Terminal Repeat Regions from Exogenous but Not Endogenous Feline Leukemia Viruses Transactivate Cellular Gene Expression.
S. K. Ghosh, P. Roy-Burman, and D. V. Faller (2000)
J. Virol. 74, 9742-9748
   Abstract »    Full Text »
Discovery of a New Endogenous Type C Retrovirus (FcEV) in Cats: Evidence for RD-114 Being an FcEVGag-Pol/Baboon Endogenous Virus BaEVEnv Recombinant.
A. C. van der Kuyl, J. T. Dekker, and J. Goudsmit (1999)
J. Virol. 73, 7994-8002
   Abstract »    Full Text »    PDF »
Inhibition of HIV-1 replication by a nonnucleoside reverse transcriptase inhibitor.
V. Merluzzi, K. Hargrave, M Labadia, K Grozinger, M Skoog, J. Wu, C. Shih, K Eckner, S Hattox, J Adams, et al. (1990)
Science 250, 1411-1413
   Abstract »    PDF »


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