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Science 21 November 1975:
Vol. 190. no. 4216, pp. 794 - 795
DOI: 10.1126/science.1198096

Articles

Science, Vol 190, Issue 4216, 794-795
Copyright © 1975 by American Association for the Advancement of Science


articles

Alcoholic hepatomegaly: accumulation of protein in the liver

E Baraona, MA Leo, SA Borowsky, and CS Lieber

The hepatomegaly that appears after long-term feeding of ethanol results in accumulation of protein that is quantitatively as important as the increase in lipid. The bulk of protein accumulated in the soluble fraction of the cell. Hepatic albumin and transferrin concentrations increase and colchicine-binding protein decreases, thus suggesting an intrahepatic retention of export proteins.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Ethanol feeding enhances age-related deterioration of the rat hepatic mitochondrion.
A. Cahill, S. Hershman, A. Davies, and P. Sykora (2005)
Am J Physiol Gastrointest Liver Physiol 289, G1115-G1123
   Abstract »    Full Text »    PDF »
FLOW CYTOMETRIC AND FLUORESCENCE MICROSCOPIC ANALYSIS OF ETHANOL-INDUCED G2+M BLOCK: ETHANOL DOSE-DEPENDENTLY DELAYS THE PROGRESSION OF THE M PHASE.
K. Mashimo, T. Haseba, and Y. Ohno (1999)
Alcohol Alcohol. 34, 300-310
   Abstract »    Full Text »    PDF »



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Science. ISSN 0036-8075 (print), 1095-9203 (online)