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Science 21 November 1975:
Vol. 190. no. 4216, pp. 790 - 792
DOI: 10.1126/science.173019
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Articles

Science, Vol 190, Issue 4216, 790-792
Copyright © 1975 by American Association for the Advancement of Science

articles

Immunosurveillance of naturally occurring feline leukemia

M Essex, A Sliski, SM Cotter, RR Jakowski, and WD Hardy Jr

When compared to their housemates that subsequently developed leukemia, cats that remained healthy had five-to tenfold higher (geometric mean) humoral antibody titers to the feline oncornavirus-associated cell membrane antigen. This is compatible with the application of the immunosurveillance hypothesis to the natural development of leukemia in an outbred mammalian species.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Isolation and Characterization of Proteins Carrying the Feline Oncornavirus-associated Cell-membrane Antigen.
H. W. Snyder Jr., K. J. Phillips, W. D. Hardy Jr., E. E. Zuckerman, M. Essex, A. H. Sliski, and J. Rhim (1980)
Cold Spring Harb Symp Quant Biol 44, 787-799
   Abstract »    PDF »
Feline oncornavirus-associated cell membrane antigen: expression in transformed nonproducer mink cells.
A. Sliski, M Essex, C Meyer, and G Todaro (1977)
Science 196, 1336-1339
   Abstract »    PDF »
Immunosurveillance of naturally occurring feline leukemia.
R. Prehn (1976)
Science 192, 915
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)