Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 14 November 1975:
Vol. 190. no. 4215, pp. 692 - 694
DOI: 10.1126/science.810890
Prev | Table of Contents | Next

Articles

Science, Vol 190, Issue 4215, 692-694
Copyright © 1975 by American Association for the Advancement of Science

articles

Effects of long-term corn consumption on brain serotonin and the response to electric shock

LD Lytle, RB Messing, L Fisher, and L Phebus

Rats fed tryptophan-poor corn diets have reduced levels of brain serotonin and show increased responsiveness to electric shock. This diet-induced hyperalgesia can be reversed by feeding the animals diets with adequate amounts of tryptophan, or by systemic injections of the amino acid.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Models and Mechanisms of Hyperalgesia and Allodynia.
J. Sandkuhler (2009)
Physiol Rev 89, 707-758
   Abstract »    Full Text »    PDF »
Effects of Tryptophan Depletion in Drug-Free Adults With Autistic Disorder.
C. McDougle, S. T. Naylor, D. J. Cohen, G. K. Aghajanian, G. R. Heninger, and L. H. Price (1996)
Arch Gen Psychiatry 53, 993-1000
   Abstract »    PDF »
Serotonin and the Neurobiology of Depression: Effects of Tryptophan Depletion in Drug-Free Depressed Patients.
P. L. Delgado, L. H. Price, H. L. Miller, R. M. Salomon, G. K. Aghajanian, G. R. Heninger, and D. S. Charney (1994)
Arch Gen Psychiatry 51, 865-874
   Abstract »    PDF »
Serotonin Function and the Mechanism of Antidepressant Action: Reversal of Antidepressant-Induced Remission by Rapid Depletion of Plasma Tryptophan.
P. L. Delgado, D. S. Charney, L. H. Price, G. K. Aghajanian, H. Landis, and G. R. Heninger (1990)
Arch Gen Psychiatry 47, 411-418
   Abstract »    PDF »
5-HIAA in the Cerebrospinal Fluid: A Biochemical Suicide Predictor?.
M. Asberg, L. Traskman, and P. Thoren (1976)
Arch Gen Psychiatry 33, 1193-1197
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)