Science, Vol 190, Issue 4214, 574-576
Copyright © 1975 by American Association for the Advancement of Science
Delayed-type hypersensitivity to sheep red blood cells: inhibition of sensitization by interferon
J De Maeyer-Guignard,
A Cachard,
and
E De Maeyer
Interferon, when given or induced 24 hours before contact of mice with sheep red blood cells, prevented sensitization, and no delayed-type hypersensitivity reaction could be elicited 4 days later, after challenge with the antigen, as shown by the absence of footpad swelling in treated animals.