Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 17 October 1975:
Vol. 190. no. 4211, pp. 284 - 285
DOI: 10.1126/science.1179209
Prev | Table of Contents | Next

Articles

Science, Vol 190, Issue 4211, 284-285
Copyright © 1975 by American Association for the Advancement of Science

articles

Hemopoietic stem cells in human peripheral blood

RD Barr, J Whang-Peng, and S Perry

A population of lymphocytes, separable from the great majority by virtue of their larger size and their failure to exhibit the rosetting characteristics of thymus-dependent lymphocytes and bursa-equivalent cells, possess true pluripotentiality. On culture in vivo they proliferate and differentiate into erythrocytic, granulocytic, and megakaryocytic progeny. This may be the first clear demonstration of the primitive progenitor blood cell in man.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Synergistic Effect of FLT-3 Ligand on the Granulocyte Colony-Stimulating Factor-Induced Mobilization of Hematopoietic Stem Cells and Progenitor Cells Into Blood in Mice.
Y. Sudo, C. Shimazaki, E. Ashihara, T. Kikuta, H. Hirai, T. Sumikuma, N. Yamagata, H. Goto, T. Inaba, N. Fujita, et al. (1997)
Blood 89, 3186-3191
   Abstract »    Full Text »    PDF »
Circulating Stem Cells -- Waxing Hematopoietic.
A. Kessinger (1995)
N. Engl. J. Med. 333, 315-317
   Full Text »
Donor-Derived Long-Term Multilineage Hematopoiesis in a Liver-Transplant Recipient.
R. H. Collins, J. Anastasi, L. Terstappen, A. Nikaein, J. Feng, J. W. Fay, G. Klintmalm, and M. J. Stone (1993)
N. Engl. J. Med. 328, 762-765
   Full Text »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)