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Science 3 October 1975:
Vol. 190. no. 4209, pp. 67 - 69
DOI: 10.1126/science.809840
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Articles

Science, Vol 190, Issue 4209, 67-69
Copyright © 1975 by American Association for the Advancement of Science

articles

Vasopressin: induced structural change in toad bladder luminal membrane

WA Kachadorian, JB Wade, and VA DiScala

Freeze-fracture electron microscopy demonstrates that vasopressin stimulation of isolated toad bladder alters the structure of the luminal membrane of granular cells. This alteration consists of an ordered aggression of intramembranous particles, and appears to be of functional significance, since the frequency of aggregation sites per area of membrane is closely correlated with vasopressin-induced osmotic water flow.


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