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Science 26 September 1975:
Vol. 189. no. 4208, pp. 1098 - 1100
DOI: 10.1126/science.1162360
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Articles

Science, Vol 189, Issue 4208, 1098-1100
Copyright © 1975 by American Association for the Advancement of Science

articles

Crustacean intestinal detergent promotes sterol solubilization

R Lester, MC Carey, JM Little, LA Cooperatein, and Dowd SR

Although crustacean tissue cholesterol content is high, Crustacea, like other arthropods; are incapable of cholesterol synthesis, and presumably are dependent for maintaining tissue cholesterol stores on the intestinal absorption of ingested sterol. A detergent, N-(N-dodecanoylsarcosyl)taurine, representative of a set of detergents synthesized by the crustacean hepatopancreas and secreted into the intestine, is capable of efficient cholesterol solubilization, and thus of promoting sterol absorption.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)