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Science 12 September 1975:
Vol. 189. no. 4206, pp. 881 - 884
DOI: 10.1126/science.1154025
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Articles

Science, Vol 189, Issue 4206, 881-884
Copyright © 1975 by American Association for the Advancement of Science

articles

Muscle activation: effects of small length changes on calcium release in single fibers

EB Ridgeway and AM Gordon

In single muscle fibers, small (1 percent) changes of length have a marked effect of both the calcium activation and the tension elicited by a constant current stimulus. The decrease in tension with shortening is accounted for almost entirely by a decrease in calcium release, rather than by changes in mechanical factors, such as filament geometry.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)