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Science 25 July 1975:
Vol. 189. no. 4199, pp. 301 - 303
DOI: 10.1126/science.1145205
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Articles

Science, Vol 189, Issue 4199, 301-303
Copyright © 1975 by American Association for the Advancement of Science

articles

Strain differences during intraventricular infusion of norepinephrine: possible role of receptor sensitivity

DS Segal, MA Geyer, and BE Weiner

Two rat strains previously shown to differ with respect to behavioral activity, regional brain tyrosine hydroxylase activity, and norepinephrine-elicited accumulation of adenosine 3', 5'-monophosphate exhibited differential behavioral responsiveness during the intraventricular infusion of norepinephrine. The results are interpreted in terms of differential catecholamine receptor sensitivity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Sensorimotor Gating and Schizophrenia: Human and Animal Model Studies.
D. L. Braff and M. A. Geyer (1990)
Arch Gen Psychiatry 47, 181-188
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Strain differences in rat brain epinephrine synthesis: regulation of alpha-adrenergic receptor number by epinephrine.
B. Perry, J. Stolk, G Vantini, R. Guchhait, and D. U'Prichard (1983)
Science 221, 1297-1299
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