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Science 25 July 1975:
Vol. 189. no. 4199, pp. 299 - 301
DOI: 10.1126/science.1145204
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Articles

Science, Vol 189, Issue 4199, 299-301
Copyright © 1975 by American Association for the Advancement of Science

articles

Supraependymal cells of hypothalamic third ventricle: identification as resident phagocytes of the brain

R Bleier, R Albrecht, and JA Cruce

Cells lying on the ventricular surface of the hypothalamic ependyma of the tegu lizard exhibit the pseudopodial and flaplike processes characteristic of macrophages found elsewhere. Since they ingest latex beads, they may be considered a resident phagocytic system of the brain. The importance of ependyma and ventricular phagocytes as a first line of defense against viral invasion of the brain, as well as their role in the pathogenesis of certain virus-related diseases, is suggested by a number of experimental and clinical observations.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Evaluation and publication of scanning electron micrographs.
J. Clark and S Glagov (1976)
Science 192, 1360-1361
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Science. ISSN 0036-8075 (print), 1095-9203 (online)