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Science 25 July 1975:
Vol. 189. no. 4199, pp. 287 - 289
DOI: 10.1126/science.1145201
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Articles

Science, Vol 189, Issue 4199, 287-289
Copyright © 1975 by American Association for the Advancement of Science

articles

Dichloroacetamide antidotes for thiocarbamate herbicides: mode of action

M Lay, JP Hubbell, and JE Casida

Thiocarbamate sulfoxides formed on metabolic sulfoxidation of thicoarbamate herbicides in plants and mammals are effective carbamoylating agents for glutathione and other tissue thiols. Dichloracetamides that protect corn from thiocarbamate herbicide injury more rapid detoxification of the thiocarbamate sulfoxides by increasing their rate of carbamoylation of glutathione through elevation of the root glutathione level and glutathione s-transferase activity.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Herbicide Safener-Binding Protein of Maize . Purification, Cloning, and Expression of an Encoding cDNA.
J. S. Scott-Craig, J. E. Casida, L. Poduje, and J. D. Walton (1998)
Plant Physiology 116, 1083-1089
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