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Science 11 July 1975:
Vol. 189. no. 4197, pp. 149 - 151
DOI: 10.1126/science.1138373
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Articles

Science, Vol 189, Issue 4197, 149-151
Copyright © 1975 by American Association for the Advancement of Science

articles

Social modification of alcohol consumption in inbred mice

CL Randall and D Lester

The strain-specific "preference" for, or "aversion" to, an alcohol solution in a choice situation on the part of C57BL and DBA mice is believed to be under genetic control. But social rearing conditions are now shown to alter the voluntary consumption of alcohol, so that DBA weanling mice housed for 7 weeks with adult C57BL mice increase--and C57BL weanling mice housed with DBA adults decrease--their alcohol intake. Although substantial and highly significant changes in alcohol self-selection occur, strain-specific phenotypes are not reversed.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)