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Science 28 March 1975:
Vol. 187. no. 4182, pp. 1203 - 1206
DOI: 10.1126/science.187.4182.1203
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Articles

Preparation of Native Chromatin and Damage Caused by Shearing

Markus Noll 1, Jean O. Thomas 2, and Roger D. Kornberg 3

1 Medical Research Council Laboratory of Molecular Biology, Cambridge, CB2 2QH, England
2 Department of Biochemistry, University of Cambridge, Cambridge, CB2 IQW, England
3 Medical Research Council Laboratory of Molecular Biology, Cambridge

Chromatin prepared by a method involving limited nuclease digestion contains the same repeating structure as chromatin in the nucleus, whereas chromatin prepared by conventional methods involving shear does not.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Nucleosome arcs and helices.
J Dubochet and M Noll (1978)
Science 202, 280-286
   Abstract »    PDF »
Domains in Chromatin Structure.
T. Igo-Kemenes and H. G. Zachau (1978)
Cold Spring Harb Symp Quant Biol 42, 109-118
   Abstract »    PDF »
The Nucleosome Core Protein.
J. O. Thomas and P. J. G. Butler (1978)
Cold Spring Harb Symp Quant Biol 42, 119-125
   Abstract »    PDF »
H1 Histone and the Condensation of Chromatin and DNA.
R. D. Cole, G. M. Lawson, and M. W. Hsiang (1978)
Cold Spring Harb Symp Quant Biol 42, 253-263
   Abstract »    PDF »
Nuclear morphometry during the cell cycle.
F Kendall, R Swenson, T Borun, J Rowinski, and C Nicolini (1977)
Science 196, 1106-1109
   Abstract »    PDF »
Ribosomal genes of Xenopus laevis: evidence of nucleosomes in transcriptionally active chromatin.
R Reeves (1976)
Science 194, 529-532
   Abstract »    PDF »
DNA structure in sheared and unsheared chromatin.
C Nicolini, R Baserga, and F Kendall (1976)
Science 192, 796-798
   Abstract »    PDF »


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