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Science 7 March 1975:
Vol. 187. no. 4179, pp. 847 - 849
DOI: 10.1126/science.1114330
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Articles

Science, Vol 187, Issue 4179, 847-849
Copyright © 1975 by American Association for the Advancement of Science

articles

Beta cell culture on synthetic capillaries: an artificial endocrine pancreas

WL Chick, AA Like, and V Lauris

Beta cells from neonatal rats were cultured on bundles of artificial capillaries perfused with tissue culture medium. Cells continued to release insulin and remained responsive to changes in glucose concentration. The quantity of insulin released was similar to that of conventional flask cultures.


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