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Science 21 February 1975:
Vol. 187. no. 4177, pp. 650 - 652
DOI: 10.1126/science.163486
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Articles

Science, Vol 187, Issue 4177, 650-652
Copyright © 1975 by American Association for the Advancement of Science

articles

Ornithine decarboxylase activity: control by cyclic nucleotides

CV Byus and DH Russell

Both exposure to cold and administration of aminophylline result in rapid increases in cyclic adenosine monophosphate (cyclic AMP) in the adrenal medulla and adrenal cortex. These increases are followed by dramatic increases in ornithine decarboxylase activity is due to new enzyme systhesis. The data suggest that the decarboxylase activity is regulated by an increase in cyclic AMP.


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