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Science 24 January 1975:
Vol. 187. no. 4173, pp. 256 - 257
DOI: 10.1126/science.163037
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Articles

Science, Vol 187, Issue 4173, 256-257
Copyright © 1975 by American Association for the Advancement of Science

articles

Reduced incidence of spontaneous mammary tumors in C3H/He mice after treatment with polyadenylate-polyuridylate

F Lacour, G Delage, and C Chianale

The effect of treatment with the double-stranded polynucleotide complex polydenylate with polyuridylate [poly(A) with poly(U)] on tumor development in C3H/He mice was evaluated. Poly(A) with poly(U) was injected in newborn females, and mice were observed for 380 days. During this experimental period 42 percent of treated mice developed tumors, while the incidence in the control group was 63 percent. This difference was statistically significant.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Review : Synthetic Polymers with Intrinsic Anticancer Activity.
L. Seymour (1991)
Journal of Bioactive and Compatible Polymers 6, 178-216
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reduced incidence of spontaneous tumors: Another statistical analysis.
J Casagrande and M. Pike (1975)
Science 190, 808-809
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