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Science 13 December 1974:
Vol. 186. no. 4168, pp. 1044 - 1045
DOI: 10.1126/science.186.4168.1044
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Articles

Antihistamines Block Radiation-Induced Taste Aversions

Carolyn J. Levy 1, Marilyn E. Carroll 1, James C. Smith 1, and Kurt G. Hofer 2

1 Departmnent of Psychology, Florida State University, Tallahassee 32306
2 Department of Biological Sciences, Florida State University

When rats are treated with an antihistamine prior to being given sublethal doses of ionizing radiation, the formation of a conditioned saccharin aversion is completely inhibited. A profound aversion could be conditioned with histamine diphosphate as the aversive stimulus. The increase in histamine production after radiation exposure represents the physiological basis of radiation-induced taste aversions.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Recall (versus recognition) of taste and immunization against aversive taste anticipations based on illness.
J. Chen and A Amsel (1980)
Science 209, 831-833
   Abstract »    PDF »
Histamine and radiation-induced taste aversion conditioning.
G. Sessions (1975)
Science 190, 402-403
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)