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Science 25 October 1974:
Vol. 186. no. 4161, pp. 365 - 366
DOI: 10.1126/science.186.4161.365
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Articles

Mammalian Hepatic Lectin

Richard J. Stockert 1, Anatol G. Morell 1, and I. Herbert Scheinberg 1

1 Division of Genetic Medicine, Department of Medicine, Albert Einstein College of Medicine, Bronx, New York 10461

A rabbit hepatic protein that specifically binds asialoglycoproteins is also a lectin that agglutinates untreated human and rabbit erythrocytes and neuraminidase-treated erythrocytes from rat, mouse, and guinea pig. Both binding of asialoglycoproteins and agglutination of erythrocytes appear to involve reaction on the same active sites of the hepatic protein.


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