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Science 13 September 1974:
Vol. 185. no. 4155, pp. 953 - 955
DOI: 10.1126/science.185.4155.953
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Articles

Isolated Brain Microvessels: A Purified, Metabolically Active Preparation from Bovine Cerebral Cortex

Klaus Brendel 1, Elias Meezan 1, and Edward C. Carlson 2

1 Department of Pharmacology, University of Arizona Medical School, Tucson 85724
2 Department of Anatomy, University of Arizona Medical School

A purified, metabolically active preparation of brain microvessels was isolated from bovine cerebral cortex by using a simple procedure involving mild disruption of the tissue by homogenization and trapping of the vessels on nylon sieves. This preparation permits in vitro metabolic and structural studies of small blood vessels.


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