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Science 26 July 1974:
Vol. 185. no. 4148, pp. 364 - 365
DOI: 10.1126/science.185.4148.364
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Articles

Octopamine: Presence in Single Neurons of Aplysia Suggests Neurotransmitter Function

Juan M. Saavedra 1, Michael J. Brownstein 1, David O. Carpenter 2, and Julius Axelrod 3

1 Laboratory of Clinical Science, National Institute of Mental Health, Bethesda, Maryland 20014
2 Neurobiology Department. Armed Forces Radiobiology Research Institute, Bethesda, Maryland 20014
3 Laboratory of Clinical Science, National Institute of Mental Health, Bethesda. Marvland 20014

Octopamine has been identified and measured in individual neurons from Aplysia californica. Neither dopamine nor norepinephrine was detected in these cells. Thus, in Aplysia there may be separate populations of catecholaminergic and monophenolaminergic cells. Octopamine may have functions of its own in the central nervous system of mollusks.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cloning and Expression of a Complementary DNA Encoding a Molluscan Octopamine Receptor That Couples to Chloride Channels in HEK293 Cells.
C. C. Gerhardt, H. C. Lodder, M. Vincent, R. A. Bakker, R. J. Planta, E. Vreugdenhil, K. S. Kits, and H. van Heerikhuizen (1997)
J. Biol. Chem. 272, 6201-6207
   Abstract »    Full Text »    PDF »
Molecular Cloning and Pharmacological Characterization of a Molluscan Octopamine Receptor.
C. C. Gerhardt, R. A. Bakker, G. J. Piek, R. J. Planta, E. Vreugdenhil, J. E. Leysen, and H. Van Heerikhuizen (1997)
Mol. Pharmacol. 51, 293-300
   Abstract »    Full Text »    PDF »
Octopamine receptors, adenosine 3',5'-monophosphate, and neural control of firefly flashing.
J. Nathanson (1979)
Science 203, 65-68
   Abstract »    PDF »
Phenylethanolamine: a new putative neurotransmitter in Aplysia.
J. Saavedra, J Ribas, J Swann, and D. Carpenter (1977)
Science 195, 1004-1006
   Abstract »    PDF »
Octopamine Neurons in Lobsters: Location, Morphology, Release of Octopamine and Possible Physiological Role.
E. A. Kravitz, P. D. Evans, B. R. Talamo, B. G. Wallace, and B. A. Battelle (1976)
Cold Spring Harb Symp Quant Biol 40, 127-133
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)