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Science 26 July 1974:
Vol. 185. no. 4148, pp. 362 - 363
DOI: 10.1126/science.185.4148.362
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Articles

Ocular Hazard from Picosecond Pulses of Nd: YAG Laser Radiation

William T. Ham Jr. 1, Harold A. Mueller 1, Arnold I. Goldman 1, Brian E. Newnam 2, L. M. Holland 2, and T. Kuwabara 3

1 Department of Biophysics, Virginia Commonwealth University, Richmond
2 L Division and H Division, Los Alamos Scientific Laboratory, Los Alamos, New Mexico 87544
3 Natioinal Eye Institute, National Institutes of Health, Bethesda, Maryland 20014

Seven rhesus monkeys (14 eyes) were exposed to 1064-nanometer radiation in single pulses of 25 to 35 picoseconds fromn a mode-locked Nd: YA G laser. Threshold injury resulted from single pulses with a mnean energy of 13 ± 3 mnicrojoules. Electron microscopy of the retina revealed that damnage was highly localized in the photoreceptor and pigmented epithelial cells at the oluter retina. Membrane disruption, distorted outer segmtzents, and abnormnal melanin granules resembling fetal premelanosomnies were observed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Thresholds for Visible Lesions in the Primate Eye Produced by Ultrashort Near-Infrared Laser Pulses.
C. P. Cain, C. A. Toth, G. D. Noojin, V. Carothers, D. J. Stolarski, and B. A. Rockwell (1999)
Invest. Ophthalmol. Vis. Sci. 40, 2343-2349
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