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Science 26 July 1974:
Vol. 185. no. 4148, pp. 360 - 361
DOI: 10.1126/science.185.4148.360
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Articles

Immediate Hypersensitivity Responses in Flatfish heat sensitive

Thelma C. Fletcher 1 and Brian A. Baldo 2

1 NERC Institute of Marine Biochemistry, A berdeen, Scotland
2 Clinical Immunology Unit, Princess Margaret Hospital, University of Western Australia, Western Australia 6008

Fungal extracts that precipitate with human C-reactive protein caused immediate erythema on subdermal injection into marine flatfish. Only species with calcium-dependent serum precipitins to these fungi showed skin reactions. Immediate hypersensitivity in a nonreactive species could be induced after injection with serum from reactive species. The transferable serum factor (or factors) was heat sensitive.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)