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Science 26 April 1974:
Vol. 184. no. 4135, pp. 480 - 482
DOI: 10.1126/science.184.4135.480
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Articles

Human Acid Phosphatase in Somatic Cell Hybrids

Gail A. P. Bruns 1 and Park S. Gerald 1

1 Clinical Genetics Division, Children's Hospital Medical Center, 300 Longwood Avenue, Boston, Massachusetts 02115

The human enzyme, lysosomal acid phosphatase ACP2, is expressed in nan-rodent somatic cell hybrids as a dimeric molecule. The human-rodent heteropolymer, as well as the human and rodent homopolymer, is associated with lysosomes in these cells. The genes specifying lysosomal acid phosphatase ACP2 and LDH A are syntenic.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)