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Science 26 April 1974:
Vol. 184. no. 4135, pp. 471 - 473
DOI: 10.1126/science.184.4135.471
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Articles

Lectin Binding Saccharides on a Parasitic Protozoan

Dennis M. Dwyer 1

1 Laboratory of Parasitology, Rockefeller University, New York 10021

Leishmania donovani promastigotes were specifically agglutinated by concanavalin A and phytohemagglutinin P. Somatic-somatic, flagellar-somatic, and flagellar-flagellar type agglutination was observed with the lectins. Enzyme-treated promastigotes gave reduced lectin agglutination reactions. The results suggest that complex saccharide moieties are randomly distributed on the surface of this organism.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Multiplication of a human parasite (Leishmania donovani) in phagolysosomes of hamster macrophages in vitro.
K. Chang and D. Dwyer (1976)
Science 193, 678-680
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Science. ISSN 0036-8075 (print), 1095-9203 (online)