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Science 26 April 1974:
Vol. 184. no. 4135, pp. 464 - 466
DOI: 10.1126/science.184.4135.464
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Articles

Lymphocyte Antigenicity Loss with Retention of Responsiveness

Gerhard Opelz 1 and Paul I. Terasaki 1

1 Department of Surgery, School of Medicine, University of California, Los Angeles 90024

During culturing at 22°C for more than 4 days, human peripheral blood lymphocytes lose their ability to stimulate allogeneic lymphocytes in mixed lymphocyte cultures. The cells retain their ability to respond to allogeneic lymphocytes or phytohemagglutinin for up to 10 days of culturing. The findings are relevant to reports on successful transplantation of cultured skin.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prolongation of islet allograft survival following in vitro culture (24 degrees C) and a single injection of ALS.
P. Lacy, J. Davie, and E. Finke (1979)
Science 204, 312-313
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Science. ISSN 0036-8075 (print), 1095-9203 (online)