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Science 8 March 1974:
Vol. 183. no. 4128, pp. 966 - 968
DOI: 10.1126/science.183.4128.966
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Articles

Mapping Human Autosomes: Evidence Supporting Assignment of Rhesus to the Short Arm of Chromosome No. 1

W. L. Marsh 1, R. S. K. Chaganti 1, Frank H. Gardner 2, Klaus Mayer 3, Peter C. Nowell 4, and James German 5

1 New York Blood Center, 310 East 67 Street, New York 10021
2 Presbyterian-University of Pennsylvania Medical Center, Philadelphia
3 Memorial Sloan-Kettering Cancer Center, New York
4 University of Pennsylvania School of Medicine, Philadelphia
5 New York Blood Center, 310 East 67 Street, New York

Rh-negative erythrocytes were found in the blood of an Rh-positive man suffering from myelofibrosis. Nucleated hemopoietic precursors were also circulating in his blood, and these cells had an abnormal chromosome complement from which identifiable chromosome segments had been deleted. Correlation of the serological and cytogenetic findings, combined with previous data, indicates that the Rhesus blood group locus is on the distal portion of the short arm of chromosome No. 1.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Prenatal Determination of Fetal RhD Type by DNA Amplification.
P. R. Bennett, C. L. V. Kim, Y. Colin, R. M. Warwick, B. Cherif-Zahar, N. M. Fisk, and J.-P. Cartron (1993)
N. Engl. J. Med. 329, 607-610
   Abstract »    Full Text »
Human Gene Mapping, Genetic Linkage, and Clinical Applications.
R. S. SPARKES, M. A. SPENCE, T. MOHANDAS, L. J. SHAPIRO, and S. J. FUNDERBURK (1980)
Ann Intern Med 93, 469-479
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Familial Turner Syndrome.
D. A. LEICHTMAN, R. D. SCHMICKEL, T. D. GELEHRTER, W. J. JUDD, M. C. WOODBURY, and K. L. MEILINGER (1978)
Ann Intern Med 89, 473-476
   Abstract »    PDF »
The status of the gene map of the human chromosomes.
V. McKusick and F. Ruddle (1977)
Science 196, 390-405
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